DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon66Cii and Tmprss4

DIOPT Version :9

Sequence 1:	NP_648217.1	Gene:	Jon66Cii / 38953	FlyBaseID:	FBgn0035887	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_038937788.1	Gene:	Tmprss4 / 367074	RGDID:	1305033	Length:	478	Species:	Rattus norvegicus

Alignment Length:	236	Identity:	75/236 - (31%)
Similarity:	115/236 - (48%)	Gaps:	31/236 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 RITNGYPAEEGKAPYTVGLGFSGGWWCGGSIIAHDWVLTAEHCIGDADSVTVYFGATWRTNAQFT 103
            |:..|..|.....|:.|.:.::....|||||:.|.|:|||.||......|     ::|:..|. :
  Rat   245 RVVGGVEASADSWPWQVSIQYNKQHVCGGSILDHHWILTAAHCFRKYLDV-----SSWKVRAG-S 303

  Fly   104 HWVGNG-------------NFIKHSSADIALIRIP-HVDFWHMVNKVELPSYNDRYNDYNEWWAV 154
            :.:||.             |.::....||||:::. .:.|...|..:.||..::........|.:
  Rat   304 NKLGNSPSLPVAKIFIAEPNPLQPKEKDIALVKLKMPLTFSGSVRPICLPFSDEELIPTMPVWVI 368

  Fly   155 ACGWGGTYD-GSPLPDYLQCVDLQIIHNSECS---GYYGSVGDNILCVRTPD-GKSTCGGDSGGP 214
              |||.|.: |..:.|.|....:|:|.::.|:   .|.|.|...:||..||. ||.||.||||||
  Rat   369 --GWGFTEENGGKMSDTLLQASVQVIDSARCNAEDAYQGEVTAGMLCAGTPQGGKDTCQGDSGGP 431

  Fly   215 LVTH-DGTKLVGVTNFGSVAGCQS-GAPAGFQRVTYHLDWI 253
            |:.| |..::||:.::|  .||.| ..|..:.:||.:||||
  Rat   432 LMYHYDKWQVVGIVSWG--YGCGSPSTPGVYTKVTAYLDWI 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon66Cii	NP_648217.1	Tryp_SPc	39..253	CDD:214473	73/234 (31%)
Jon66Cii	NP_648217.1	Tryp_SPc	40..256	CDD:238113	74/235 (31%)
Tmprss4	XP_038937788.1	LDLa	99..133	CDD:238060
		SRCR_2	149..238	CDD:413346
		Tryp_SPc	245..470	CDD:214473	73/234 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910