DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon66Cii and TMPRSS7

DIOPT Version :9

Sequence 1:	NP_648217.1	Gene:	Jon66Cii / 38953	FlyBaseID:	FBgn0035887	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_001382436.1	Gene:	TMPRSS7 / 344805	HGNCID:	30846	Length:	843	Species:	Homo sapiens

Alignment Length:	245	Identity:	69/245 - (28%)
Similarity:	108/245 - (44%)	Gaps:	38/245 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 RITNGYPAEEGKAPYTVGLGFSGGWWCGGSIIAHDWVLTAEHC-----IGDADSVTVYFGATWRT 98
            ||..|....||..|:.|.|.|.|..:||.|:|:.:|:|:|.||     :.|....|.:.|...:.
Human   605 RIIGGTDTLEGGWPWQVSLHFVGSAYCGASVISREWLLSAAHCFHGNRLSDPTPWTAHLGMYVQG 669

  Fly    99 NAQF--------THWVGNGNFIKHSSADIALIRIPHVDFW-----HMVNKVELPSYNDRYNDYNE 150
            ||:|        .|...|.....:   ||||:::...  |     .::..:.:|....|.....:
Human   670 NAKFVSPVRRIVVHEYYNSQTFDY---DIALLQLSIA--WPETLKQLIQPICIPPTGQRVRSGEK 729

  Fly   151 WWAVACGWGGTYD----GSPLPDYLQCVDLQIIHNSECSGYYGSVGDNILCVRTPDGK-STCGGD 210
            .|..  |||..::    ||.:   ||..::::|..:.|...||.:...:||.....|| ..|.||
Human   730 CWVT--GWGRRHEADNKGSLV---LQQAEVELIDQTLCVSTYGIITSRMLCAGIMSGKRDACKGD 789

  Fly   211 SGGPLVTH---DGT-KLVGVTNFGSVAGCQSGAPAGFQRVTYHLDWIRDH 256
            |||||...   ||. .|.|:.::|..:| :...|..:.||:..:.||..:
Human   790 SGGPLSCRRKSDGKWILTGIVSWGHGSG-RPNFPGVYTRVSNFVPWIHKY 838

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon66Cii	NP_648217.1	Tryp_SPc	39..253	CDD:214473	67/240 (28%)
Jon66Cii	NP_648217.1	Tryp_SPc	40..256	CDD:238113	68/242 (28%)
TMPRSS7	NP_001382436.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	27..67
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910