DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon66Cii and OVCH1

DIOPT Version :9

Sequence 1:	NP_648217.1	Gene:	Jon66Cii / 38953	FlyBaseID:	FBgn0035887	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_024304736.1	Gene:	OVCH1 / 341350	HGNCID:	23080	Length:	1120	Species:	Homo sapiens

Alignment Length:	251	Identity:	79/251 - (31%)
Similarity:	115/251 - (45%)	Gaps:	29/251 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 LTPVHTKDMQGRITNGYPAEEGKAPYTVGLGFSGGWWCGGSIIAHDWVLTAEHCI---GDADSVT 89
            :.|...:.:..||..|..|.....|:.|||.|.|.:.|||:||...|:|||.||:   .:..|.|
Human   598 IPPFSPQWLSRRIAGGEEACPHCWPWQVGLRFLGDYQCGGAIINPVWILTAAHCVQLKNNPLSWT 662

  Fly    90 VYFGATWRTNAQFTHWVGNG-NFIKHS-------SADIALIRIPH-VDFWHMVNKVELP-SYNDR 144
            :..|...|...:.|..|... :.|.|.       .:|||||::.. :::..:|..|.|| |....
Human   663 IIAGDHDRNLKESTEQVRRAKHIIVHEDFNTLSYDSDIALIQLSSPLEYNSVVRPVCLPHSAEPL 727

  Fly   145 YNDYNEWWAVACGWGGTYDGSPLPDYLQCVDLQIIHNSEC-----SGYYGSVGDNILCV--RTPD 202
            ::  :|..||. |||.......|...||.:.:.::....|     |.:.|.:.:.::|.  ....
Human   728 FS--SEICAVT-GWGSISADGGLASRLQQIQVHVLEREVCEHTYYSAHPGGITEKMICAGFAASG 789

  Fly   203 GKSTCGGDSGGPLV-THDGTKLV--GVTNFGSVAGC-QSGAPAGFQRVTYHLDWIR 254
            .|..|.|||||||| .|:....|  |:.::|  ||| |...|..|.||...||||:
Human   790 EKDFCQGDSGGPLVCRHENGPFVLYGIVSWG--AGCVQPWKPGVFARVMIFLDWIQ 843

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon66Cii	NP_648217.1	Tryp_SPc	39..253	CDD:214473	76/237 (32%)
Jon66Cii	NP_648217.1	Tryp_SPc	40..256	CDD:238113	77/239 (32%)
OVCH1	XP_024304736.1	Tryp_SPc	58..294	CDD:238113
		CUB	336..444	CDD:238001
		CUB	454..565	CDD:238001
		Tryp_SPc	610..845	CDD:238113	77/239 (32%)
		CUB	881..978	CDD:238001
		CUB	1017..1119	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910