DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon66Cii and OVCH2

DIOPT Version :9

Sequence 1:	NP_648217.1	Gene:	Jon66Cii / 38953	FlyBaseID:	FBgn0035887	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_016873148.1	Gene:	OVCH2 / 341277	HGNCID:	29970	Length:	569	Species:	Homo sapiens

Alignment Length:	288	Identity:	81/288 - (28%)
Similarity:	123/288 - (42%)	Gaps:	44/288 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 AILALAVASASGATMPRLATEKLTPVHTKDMQGRITNGYPAEEGKAPYTVGLGFSGGWWCGGSII 70
            |.|:|..|.:.|.::     .|:.|.:..::..||..|...|:|..|:.|.|.......|||||:
Human    27 ATLSLPKAPSCGQSL-----VKVQPWNYFNIFSRILGGSQVEKGSYPWQVSLKQRQKHICGGSIV 86

  Fly    71 AHDWVLTAEHCIGDADSVTVY------FGATWRTNAQFTHWVGNGNFIKHSSA------DIALIR 123
            :..||:||.|||.:.:.|:..      :..:.....:.|..:.......|.|.      ||||::
Human    87 SPQWVITAAHCIANRNIVSTLNVTAGEYDLSQTDPGEQTLTIETVIIHPHFSTKKPMDYDIALLK 151

  Fly   124 IPHV-DFWHMVNKVELPSYNDRYNDYNEWWAVACGWGGTYDGSPLPDYLQCVDLQIIHNSECSGY 187
            :... .|.|.|..:.||...:::.  ..:.....|||...:|..|...||.|:|.|:...||...
Human   152 MAGAFQFGHFVGPICLPELREQFE--AGFICTTAGWGRLTEGGVLSQVLQEVNLPILTWEECVAA 214

  Fly   188 YGSV-----GDNILCVRTPD-GKSTCGGDSGGPLVTHD---GTKLVGVTNFGSVAGC-------- 235
            ..::     |...||...|| |:..|.|||||.|:..:   ...|.|||::|  .||
Human   215 LLTLKRPISGKTFLCTGFPDGGRDACQGDSGGSLMCRNKKGAWTLAGVTSWG--LGCGRGWRNNV 277

  Fly   236 ---QSGAPAGFQRVTYHLDWIRDH--TG 258
               ..|:|..|..::..|.||.:|  ||
Human   278 RKSDQGSPGIFTDISKVLPWIHEHIQTG 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon66Cii	NP_648217.1	Tryp_SPc	39..253	CDD:214473	69/246 (28%)
Jon66Cii	NP_648217.1	Tryp_SPc	40..256	CDD:238113	70/248 (28%)
OVCH2	XP_016873148.1	Tryp_SPc	55..298	CDD:214473	69/246 (28%)
		Tryp_SPc	56..301	CDD:238113	70/248 (28%)
		CUB	320..424	CDD:238001
		CUB	435..546	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910