DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon66Cii and prss60.3

DIOPT Version :9

Sequence 1:	NP_648217.1	Gene:	Jon66Cii / 38953	FlyBaseID:	FBgn0035887	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_002662541.2	Gene:	prss60.3 / 335152	ZFINID:	ZDB-GENE-030131-7092	Length:	330	Species:	Danio rerio

Alignment Length:	247	Identity:	87/247 - (35%)
Similarity:	118/247 - (47%)	Gaps:	34/247 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 PVHTKDMQGRITNGYPAEEGKAPYTVGLGFS--GGWWCGGSIIAHDWVLTAEHCIGDADSVT--V 90
            |::|     ||..|..|..|..|:.|.|...  ||.:||||:|:.:|||||.||:......|  |
Zfish    31 PLNT-----RIVGGVNASPGSWPWQVSLHSPKYGGHFCGGSLISSEWVLTAAHCLSGVSETTLVV 90

  Fly    91 YFGATWRTNAQFTHWVGNGNFIK---HSS-------ADIALIRIPH-VDFWHMVNKVELPSYNDR 144
            |.|.  ||......:..:.|..|   |||       .||||:|:.. |.|.:.:..|.|.:.|..
Zfish    91 YLGR--RTQQGINIYETSRNVAKSFVHSSYNSNTNDNDIALLRLSSAVTFTNYIRPVCLAAQNSV 153

  Fly   145 YNDYNEWWAVACGWGGTYDG--SPLPDYLQCVDLQIIHNSECSGYYGS--VGDNILCV-RTPDGK 204
            |:.....|..  |||....|  .|.|..||...:.::.|..|:...||  |.:|::|. .|..||
Zfish   154 YSAGTSSWIT--GWGDIQAGVNLPAPGILQETMIPVVANDRCNALLGSGTVTNNMICAGLTQGGK 216

  Fly   205 STCGGDSGGPLVTHDGTKLV--GVTNFGSVAGC-QSGAPAGFQRVTYHLDWI 253
            .||.||||||:||...|..|  |:|::|  .|| ...:|..:.||:.:..||
Zfish   217 DTCQGDSGGPMVTRLCTVWVQAGITSWG--YGCADPNSPGVYTRVSQYQSWI 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon66Cii	NP_648217.1	Tryp_SPc	39..253	CDD:214473	83/236 (35%)
Jon66Cii	NP_648217.1	Tryp_SPc	40..256	CDD:238113	84/237 (35%)
prss60.3	XP_002662541.2	Tryp_SPc	36..269	CDD:238113	84/237 (35%)
prss60.3	XP_002662541.2	Somatomedin_B	294..328	CDD:321959
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000