DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon66Cii and tmprss4b

DIOPT Version :9

Sequence 1:	NP_648217.1	Gene:	Jon66Cii / 38953	FlyBaseID:	FBgn0035887	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_001119849.1	Gene:	tmprss4b / 327651	ZFINID:	ZDB-GENE-030131-5862	Length:	432	Species:	Danio rerio

Alignment Length:	246	Identity:	68/246 - (27%)
Similarity:	101/246 - (41%)	Gaps:	49/246 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 QGRITNGYPAEEGKAPYTVGLGFSGGWWCGGSIIAHDWVLTAEHCIGDADSVTVYFGATWRTNAQ 101
            :.||..|........|:.|.|.|:....||||:::..|:::|.||.            |.||. :
Zfish   199 EDRIVGGVETSIEHWPWQVSLQFNHRHMCGGSLLSTSWIISAAHCF------------TGRTQ-E 250

  Fly   102 FTHW---VGNGNFIKHSSADIALIRIPHVDFWHMVNKVE--------------------LPSYND 143
            .:.|   :|....:......:.:|.| |.|:..:.|..:                    ||.:..
Zfish   251 LSRWTVVLGQTKVMDVVGVSVDMIVI-HKDYNRLTNDFDIAMLKLTWPVKTGESILPVCLPPHQL 314

  Fly   144 RYNDYNEWWAVACGWGGTYDGSPLPDYLQCVDLQIIHNSECSG---YYGSVGDNILCVRTPDGK- 204
            ...|    ..|..|||...:|..||..||...:.:::.||||.   |..|:...:||.....|.
Zfish   315 AIKD----MLVVTGWGLLKEGGALPTVLQKASVPLVNRSECSKPTIYSSSITPRMLCAGFLQGNV 375

  Fly   205 STCGGDSGGPLV-THDGTKLVGVTNFGSVAGC-QSGAPAGFQRVTYHLDWI 253
            ..|.|||||||| .....:|:|:.::|  .|| :.|.|..:..||..||||
Zfish   376 DACQGDSGGPLVYLSSRWQLIGIVSWG--VGCAREGKPGVYADVTQLLDWI 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon66Cii	NP_648217.1	Tryp_SPc	39..253	CDD:214473	66/242 (27%)
Jon66Cii	NP_648217.1	Tryp_SPc	40..256	CDD:238113	67/243 (28%)
tmprss4b	NP_001119849.1	SRCR_2	100..179	CDD:292133
		SRCR	105..>175	CDD:278931
		Tryp_SPc	201..424	CDD:214473	66/242 (27%)
		Tryp_SPc	202..427	CDD:238113	67/243 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000