DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon66Cii and Tmprss3

DIOPT Version :9

Sequence 1:	NP_648217.1	Gene:	Jon66Cii / 38953	FlyBaseID:	FBgn0035887	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_038954650.1	Gene:	Tmprss3 / 309665	RGDID:	1310135	Length:	454	Species:	Rattus norvegicus

Alignment Length:	280	Identity:	83/280 - (29%)
Similarity:	121/280 - (43%)	Gaps:	43/280 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 IAILALAVASASGATMPRLATEKLTPVHTK-DMQGRITNGYPAEEGKAPYTVGLGFSGGWWCGGS 68
            :..|..:|....|.|...:.|.|.:....: ....||..|..:...:.|:.|.|.|.|...||||
  Rat   181 VTALHHSVYMREGCTSGHVVTLKCSACGMRTGYSPRIVGGNVSSLTQWPWQVSLQFQGYHLCGGS 245

  Fly    69 IIAHDWVLTAEHCIGDADSVTVYFGATWRTNAQF---------THWVGNGNFIKHS-------SA 117
            :|...|::||.||:.|     :|...:|......         :|.|  ...|.||       ..
  Rat   246 VITPLWIVTAAHCVYD-----LYHPKSWTVQVGLVSLMDSPVPSHLV--EKIIYHSKYKPKRLGN 303

  Fly   118 DIALIRIPH-VDFWHMVNKVELPSYNDRYNDYNEWWAVACGWGGTYDG----SPLPDYLQCVDLQ 177
            ||||:::.. :.|...:..:.||:..:.:.|....|  ..|||.|.||    ||:   |....:.
  Rat   304 DIALMKLSEPLTFDETIQPICLPNSEENFPDGKLCW--TSGWGATEDGAGDASPV---LNHAAVP 363

  Fly   178 IIHNSECSG---YYGSVGDNILCV-RTPDGKSTCGGDSGGPLVTHDGT--KLVGVTNFGSVAGC- 235
            :|.|..|:.   |.|.:..::||. ....|..:|.||||||||..:..  ||||.|:||  .||
  Rat   364 LISNKICNHRDVYGGIISPSMLCAGYLKGGVDSCQGDSGGPLVCQERRLWKLVGATSFG--IGCA 426

  Fly   236 QSGAPAGFQRVTYHLDWIRD 255
            :...|..:.|:|..||||.:
  Rat   427 EVNKPGVYTRITSFLDWIHE 446

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon66Cii	NP_648217.1	Tryp_SPc	39..253	CDD:214473	75/241 (31%)
Jon66Cii	NP_648217.1	Tryp_SPc	40..256	CDD:238113	76/244 (31%)
Tmprss3	XP_038954650.1	LDLa	74..107	CDD:238060
		SRCR_2	112..211	CDD:406055	6/29 (21%)
		Tryp_SPc	216..444	CDD:214473	75/241 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910