DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Jon66Cii and Tmprss11d

DIOPT Version :9

Sequence 1:	NP_648217.1	Gene:	Jon66Cii / 38953	FlyBaseID:	FBgn0035887	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	NP_663536.1	Gene:	Tmprss11d / 231382	MGIID:	2385221	Length:	417	Species:	Mus musculus

Alignment Length:	240	Identity:	81/240 - (33%)
Similarity:	116/240 - (48%)	Gaps:	26/240 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 RITNGYPAEEGKAPYTVGLGFSGGWWCGGSIIAHDWVLTAEHCIGDADSV---TVYFGATW---- 96
            ||..|..||.|..|:.|.|..:....|||::|::.|||||.||.....:.   |..||.:.
Mouse   185 RIIGGMQAEPGDWPWQVSLQLNNVHHCGGALISNMWVLTAAHCFKSYPNPQYWTATFGVSTMSPR 249

  Fly    97 ---RTNAQFTHWVGNGNFIKHSSADIALIRIPH-VDFWHMVNKVELPSYNDRYNDYNEWWAVACG 157
               |..|...|   :|........|||::::.. |.|...:::|.||:...  |......|...|
Mouse   250 LRVRVRAILAH---DGYSSVTRDNDIAVVQLDRSVAFSRNIHRVCLPAATQ--NIIPGSVAYVTG 309

  Fly   158 WGG-TYDGSPLPDYLQCVDLQIIHNSEC---SGYYGSVGDNILCVRTPDGK-STCGGDSGGPLVT 217
            ||. ||.|:.:.: |:..:::||.:.||   :||.|||...:||.....|. ..|.||||||||.
Mouse   310 WGSLTYGGNAVTN-LRQGEVRIISSEECNTPAGYSGSVLPGMLCAGMRSGAVDACQGDSGGPLVQ 373

  Fly   218 HDGTKL---VGVTNFGSVAGCQSGAPAGFQRVTYHLDWIRDHTGI 259
            .|..:|   ||:.::|...|..: .|..:.|||.:.:|||..|||
Mouse   374 EDSRRLWFVVGIVSWGYQCGLPN-KPGVYTRVTAYRNWIRQQTGI 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon66Cii	NP_648217.1	Tryp_SPc	39..253	CDD:214473	75/232 (32%)
Jon66Cii	NP_648217.1	Tryp_SPc	40..256	CDD:238113	77/234 (33%)
Tmprss11d	NP_663536.1	SEA	48..140	CDD:279699
		Tryp_SPc	185..411	CDD:214473	75/232 (32%)
		Tryp_SPc	186..414	CDD:238113	77/234 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910