DRSC/TRiP Functional Genomics Resources

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Protein Alignment Jon66Cii and F12

DIOPT Version :9

Sequence 1:NP_648217.1 Gene:Jon66Cii / 38953 FlyBaseID:FBgn0035887 Length:262 Species:Drosophila melanogaster
Sequence 2:NP_000496.2 Gene:F12 / 2161 HGNCID:3530 Length:615 Species:Homo sapiens


Alignment Length:256 Identity:75/256 - (29%)
Similarity:110/256 - (42%) Gaps:51/256 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    39 RITNGYPAEEGKAPYTVGLGFSGGWWCGGSIIAHDWVLTAEHCIGD---ADSVTVYFGATWRTNA 100
            |:..|..|..|..||...| :.|..:|.||:||..|||||.||:.|   .:.:||..|...|.::
Human   372 RVVGGLVALRGAHPYIAAL-YWGHSFCAGSLIAPCWVLTAAHCLQDRPAPEDLTVVLGQERRNHS 435

  Fly   101 -QFTHWVGNGNFIKHSS-------ADIALIRI------------PHVDFWHMVNKVELPSYNDRY 145
             :....:...::..|.:       .|:||:|:            |:      |..|.|||...|.
Human   436 CEPCQTLAVRSYRLHEAFSPVSYQHDLALLRLQEDADGSCALLSPY------VQPVCLPSGAARP 494

  Fly   146 NDYNEWWAVAC---GWGGTYDGS-PLPDYLQCVDLQIIHNSECSG---YYGSVGDNILCVR-TPD 202
            ::     ...|   |||..::|: ....:||...:..:....||.   :..|:...:||.. ...
Human   495 SE-----TTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVHGSSILPGMLCAGFLEG 554

  Fly   203 GKSTCGGDSGGPLVTHDGT-----KLVGVTNFGSVAGC-QSGAPAGFQRVTYHLDWIRDHT 257
            |...|.||||||||..|..     .|.|:.::||  || ....|..:..|.|:|.|||:||
Human   555 GTDACQGDSGGPLVCEDQAAERRLTLQGIISWGS--GCGDRNKPGVYTDVAYYLAWIREHT 613

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Jon66CiiNP_648217.1 Tryp_SPc 39..253 CDD:214473 70/250 (28%)
Tryp_SPc 40..256 CDD:238113 72/252 (29%)
F12NP_000496.2 FN2 41..88 CDD:128373
EGF_CA 96..131 CDD:238011
FN1 133..173 CDD:238018
EGF 178..206 CDD:278437
Kringle 217..295 CDD:278480
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 298..359
Tryp_SPc 372..609 CDD:214473 70/250 (28%)
Tryp_SPc 373..612 CDD:238113 72/252 (29%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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