DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon66Cii and F11

DIOPT Version :9

Sequence 1:	NP_648217.1	Gene:	Jon66Cii / 38953	FlyBaseID:	FBgn0035887	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_005262878.1	Gene:	F11 / 2160	HGNCID:	3529	Length:	626	Species:	Homo sapiens

Alignment Length:	267	Identity:	83/267 - (31%)
Similarity:	122/267 - (45%)	Gaps:	36/267 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 SGATMPRLATEKLTPVHTKDMQGRITNGYPAEEGKAPYTVGLGFSG---GWWCGGSIIAHDWVLT 77
            ||.|: ||.  |:....|..::.||..|..:..|:.|:.|.|..:.   ...||||||.:.|:||
Human   368 SGYTL-RLC--KMDNECTTKIKPRIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILT 429

  Fly    78 AEHCIGDADS---VTVYFGATWRTN-AQFTHWVGNGNFIKH-------SSADIALIRI-PHVDFW 130
            |.||....:|   :.||.|...::. .:.|.:.|....|.|       |..||||::: ..|::.
Human   430 AAHCFYGVESPKILRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAESGYDIALLKLETTVNYT 494

  Fly   131 HMVNKVELPSYNDRYNDYNEWWAVACGWGGTYDGSPLPDYLQCVDLQIIHNSECSGYY--GSVGD 193
            .....:.|||..||...|.:.|..  |||.......:.:.||...:.::.|.||...|  ..:..
Human   495 DSQRPICLPSKGDRNVIYTDCWVT--GWGYRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITH 557

  Fly   194 NILCVRTPD-GKSTCGGDSGGPL------VTHDGTKLVGVTNFGSVAGC-QSGAPAGFQRVTYHL 250
            .::|....: ||..|.|||||||      |.|    |||:|::|.  || |...|..:..|..::
Human   558 KMICAGYREGGKDACKGDSGGPLSCKHNEVWH----LVGITSWGE--GCAQRERPGVYTNVVEYV 616

  Fly   251 DWIRDHT 257
            |||.:.|
Human   617 DWILEKT 623

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon66Cii	NP_648217.1	Tryp_SPc	39..253	CDD:214473	73/238 (31%)
Jon66Cii	NP_648217.1	Tryp_SPc	40..256	CDD:238113	74/240 (31%)
F11	XP_005262878.1	APPLE	20..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	291..375	CDD:128519	4/7 (57%)
		Tryp_SPc	388..619	CDD:214473	73/238 (31%)
		Tryp_SPc	389..619	CDD:238113	72/237 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910