DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon66Cii and Tmprss13

DIOPT Version :9

Sequence 1:	NP_648217.1	Gene:	Jon66Cii / 38953	FlyBaseID:	FBgn0035887	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_006510195.1	Gene:	Tmprss13 / 214531	MGIID:	2682935	Length:	561	Species:	Mus musculus

Alignment Length:	249	Identity:	80/249 - (32%)
Similarity:	108/249 - (43%)	Gaps:	47/249 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 MQGRITNGYPAEEGKAPYTVGLGFSGGWWCGGSIIAHDWVLTAEHCIGDADSVT---------VY 91
            |.|||..|....|.|.|:.|.|.|.....|||::|...|||||.||.    .||         ||
Mouse   316 MTGRIVGGALTSESKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCF----FVTREKLLEGWKVY 376

  Fly    92 FGATWRTN-------AQFTHWVGNGNFI-KHSSADIALIRI--PHVDFWHMVNKVELPSYNDRYN 146
            .|.   :|       |..:..:.|||:. :....||||||:  |.....| ::...||.:...:.
Mouse   377 AGT---SNLHQLPEAASISQIIINGNYTDEQDDYDIALIRLSKPLTLSAH-IHPACLPMHGQTFG 437

  Fly   147 DYNEWWAVACGWGGTYDGSPLPDYLQCVDLQIIHNSECSGYYGSVGDNILCVRTP---------D 202
            .....|....|.....|....| :|:.|.:.:|...:|:.|.  |.|:.|   ||         .
Mouse   438 LNETCWITGFGKTKETDEKTSP-FLREVQVNLIDFKKCNDYL--VYDSYL---TPRMMCAGDLRG 496

  Fly   203 GKSTCGGDSGGPLVTHDGTK--LVGVTNFGSVAGC-QSGAPAGFQRVTYHLDWI 253
            |:.:|.||||||||.....:  |.|||::|:  || |...|..:.:||..|.||
Mouse   497 GRDSCQGDSGGPLVCEQNNRWYLAGVTSWGT--GCGQKNKPGVYTKVTEVLPWI 548

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon66Cii	NP_648217.1	Tryp_SPc	39..253	CDD:214473	76/244 (31%)
Jon66Cii	NP_648217.1	Tryp_SPc	40..256	CDD:238113	77/245 (31%)
Tmprss13	XP_006510195.1	PHA03378	<6..>122	CDD:223065
		LDLa	<204..220	CDD:238060
		SRCR_2	225..314	CDD:373897
		Tryp_SPc	319..548	CDD:214473	76/244 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910