DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Jon66Cii and AgaP_AGAP001365

DIOPT Version :9

Sequence 1:	NP_648217.1	Gene:	Jon66Cii / 38953	FlyBaseID:	FBgn0035887	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_321778.5	Gene:	AgaP_AGAP001365 / 1281817	VectorBaseID:	AGAP001365	Length:	608	Species:	Anopheles gambiae

Alignment Length:	267	Identity:	73/267 - (27%)
Similarity:	117/267 - (43%)	Gaps:	55/267 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 LTPVHTKDMQGRITNGYPAEEGKAPYTVGLGFSGGWWCGGSIIAHDWVLTAEHCIG--------D 84
            |.||.|: ::.||..|..:.:|:.|:.|.:.....:.||||||...|:|||.||:.        |
Mosquito   353 LEPVGTR-IRSRIIGGVTSNQGEHPWHVAIYLDEEYQCGGSIIGRRWILTAAHCLTRQNTNETLD 416

  Fly    85 ADSVTVYFGAT---------WRTNAQFTHWVGNGNFIKHS-------SADIALIRIP-HVDFWHM 132
            .|...||.|..         :||..:         .|.|.       :.||.|:|:. ::.:...
Mosquito   417 VDLFRVYTGIIDISTIDDHFYRTADE---------VIVHRDYNPVMYTTDIGLLRLKRNITYNSF 472

  Fly   133 VNKVELPSYNDRYNDYNEWW---AVACGWGGTYDGSPLPDYLQCVDLQIIHNSECS----GYYG- 189
            :..|.|  || |..|.:.::   ....|||...|| .:.:.|..:::.::....||    .:.|
Mosquito   473 IKPVCL--YN-RTVDISTFYGREGKVTGWGFNRDG-VISNVLNYLEVPVVSQKMCSQRNVQFNGV 533

  Fly   190 -SVGDNILCVRTPDGKSTCGGDSGGPLVTHDGTK--LVGVTNFG----SVAGCQSGAPAGFQRVT 247
             :||:: .|....||.|.|.|||||.||..:|.:  :.|:.:..    ::..|.....:.|..|:
Mosquito   534 LAVGES-FCAGHADGNSVCNGDSGGGLVFAEGPRYYVRGIVSISAQRRNLLLCDPNQYSVFTDVS 597

  Fly   248 YHLDWIR 254
            ..|:|||
Mosquito   598 KFLNWIR 604

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon66Cii	NP_648217.1	Tryp_SPc	39..253	CDD:214473	66/253 (26%)
Jon66Cii	NP_648217.1	Tryp_SPc	40..256	CDD:238113	68/255 (27%)
AgaP_AGAP001365	XP_321778.5	GD_N	42..144	CDD:292649
		GD_N	190..297	CDD:292649
		Tryp_SPc	363..603	CDD:214473	66/253 (26%)
		Tryp_SPc	364..606	CDD:238113	68/255 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910