DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Jon66Cii and AgaP_AGAP008808

DIOPT Version :9

Sequence 1:	NP_648217.1	Gene:	Jon66Cii / 38953	FlyBaseID:	FBgn0035887	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_557970.3	Gene:	AgaP_AGAP008808 / 1275666	VectorBaseID:	AGAP008808	Length:	574	Species:	Anopheles gambiae

Alignment Length:	270	Identity:	64/270 - (23%)
Similarity:	104/270 - (38%)	Gaps:	64/270 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 ITNGYPAEEGKAPYTVGLGFSGG----WWCGGSIIAHDWVLTAEHCIG------DADSVTVYFGA 94
            |.||..|:.|..|:...:....|    :.|||||:..:.:|||.||:.      .|..|:|:.|.
Mosquito    44 IHNGVDAKAGHWPWHAAIFHGNGRQEEYQCGGSILDQNTILTASHCVYTHKSVISAARVSVHVGQ 108

  Fly    95 T-WRTNAQFTHWVGNGNFIKHS-------SADIALIR----------IPHVDFWHMVNKVELPSY 141
            . .:..:::|...|..:.|.|.       :.||||::          :..|..|.|
Mosquito   109 IHLKETSEYTQIHGVQDIILHPEFNSNSFNNDIALLKLSTNITMTKYVQPVCLWTM--------- 164

  Fly   142 NDRYNDYNEWWAVACGWGGTYDGSPLPDY-----------LQCVDLQIIHNSECSGYYGSVGDNI 195
                 |.|:...|  |..||..|..|.::           :..||......|:.:.:...:...:
Mosquito   165 -----DSNQEMIV--GKNGTIVGFGLNEHDVVSDQLKQALVGVVDALTCIKSDRAAFGPVLTSEM 222

  Fly   196 LCVRTPDGKSTCGGDSGGPLVTHDGTK--LVGVTNF----GSVAGCQSGAPAGFQRVTYHLDWIR 254
            .|.:...|...|.|||||.:....|.|  :.|:.:|    |:...|.......:..|..:|:||:
Mosquito   223 FCGKGRTGVGACNGDSGGGMFFEVGGKWFVRGLVSFTPLRGNTGLCDPLKYTAYTDVAKYLEWIK 287

  Fly   255 ---DHTGIAY 261
               ||..::|
Mosquito   288 QYIDHRVLSY 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon66Cii	NP_648217.1	Tryp_SPc	39..253	CDD:214473	59/257 (23%)
Jon66Cii	NP_648217.1	Tryp_SPc	40..256	CDD:238113	61/263 (23%)
AgaP_AGAP008808	XP_557970.3	Tryp_SPc	44..288	CDD:238113	61/259 (24%)
		Tryp_SPc	46..286	CDD:214473	58/255 (23%)
		Tryp_SPc	324..566	CDD:304450
		Tryp_SPc	330..566	CDD:214473
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910