DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon66Cii and tmprss2.15

DIOPT Version :9

Sequence 1:	NP_648217.1	Gene:	Jon66Cii / 38953	FlyBaseID:	FBgn0035887	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_031752206.1	Gene:	tmprss2.15 / 101732233	XenbaseID:	XB-GENE-22065943	Length:	504	Species:	Xenopus tropicalis

Alignment Length:	246	Identity:	74/246 - (30%)
Similarity:	112/246 - (45%)	Gaps:	39/246 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 MQGRITNGYPAEEGKAPYTVGLGFSGG---WWCGGSIIAHDWVLTAEHCI-GD----------AD 86
            :..||..|.||..|..|:.|.|....|   :.||||||...|::||.||: |.          |.
Frog   261 VDSRIVGGTPASVGDWPWQVELLKLVGTSIYLCGGSIITPHWIVTAAHCVYGSTSTPSAFKVFAG 325

  Fly    87 SVTV--YFGATWRTNAQFTHWVGNGNFIKHSS----ADIALIRI-PHVDFWHMVNKVELPSYNDR 144
            |:|:  |:.|.:.......|       ..:||    .|:||::: ..:.|...:..|.||:....
Frog   326 SLTIQSYYSAGYTVERALVH-------PSYSSYTQIYDVALLKLTAALVFTTNLRPVCLPNVGMP 383

  Fly   145 YNDYNEWWAVACGWGGTYDGSPLPDYLQCVDLQIIHNSECSG---YYGSVGDNILCV-RTPDGKS 205
            :.:....|  ..|||.|.:|..:...|....:.||.::.|:.   |.|::...::|. ....|..
Frog   384 WAEGQPCW--ISGWGTTAEGGSISKNLMAASVPIISSTTCNQAAVYGGAISSTMMCAGYLSGGTD 446

  Fly   206 TCGGDSGGPLVTHDGTK--LVGVTNFGSVAGC-QSGAPAGFQRVTYHLDWI 253
            ||.|||||||||...:.  |||.|::|  .|| ::..|..:..||..::||
Frog   447 TCQGDSGGPLVTKTNSLWWLVGDTSWG--YGCARAYKPGVYGNVTVFIEWI 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon66Cii	NP_648217.1	Tryp_SPc	39..253	CDD:214473	72/241 (30%)
Jon66Cii	NP_648217.1	Tryp_SPc	40..256	CDD:238113	73/242 (30%)
tmprss2.15	XP_031752206.1	LDLa	93..121	CDD:238060
		SRCR_2	164..259	CDD:406055
		Tryp_SPc	265..498	CDD:238113	73/242 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910