DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Jon66Cii and klkb1

DIOPT Version :9

Sequence 1:	NP_648217.1	Gene:	Jon66Cii / 38953	FlyBaseID:	FBgn0035887	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_002934450.3	Gene:	klkb1 / 100486524	XenbaseID:	XB-GENE-985051	Length:	629	Species:	Xenopus tropicalis

Alignment Length:	249	Identity:	77/249 - (30%)
Similarity:	110/249 - (44%)	Gaps:	37/249 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 RITNGYPAEEGKAPYTVG--LGFSGGW---WCGGSIIAHDWVLTAEHCIGD---ADSVTVYFGAT 95
            ||..|..:..|:.|:.|.  |..:..:   .||||||::.|::||.||...   .....:|.|..
Frog   390 RIVGGTDSVLGEWPWQVSMHLRLTASYKKHACGGSIISNQWIVTAAHCFAMHPLPQMWIIYSGVV 454

  Fly    96 WRTN-AQFT------------HWVGNGNFIKHSSADIALIRI-PHVDFWHMVNKVELPSYNDRYN 146
            ..:| .|.|            |:.|.||     ..||||::: ..:.|......:.||.....:.
Frog   455 KLSNITQSTPFSETEQIIIHPHYTGAGN-----GTDIALLKLKTPISFNDHQKAICLPPREPTFV 514

  Fly   147 DYNEWWAVACGWGGTYDGSPLPDYLQCVDLQIIHNSECSGYYGS--VGDNILCVRTPDGK-STCG 208
            ..|..|..  |||.|.:...|.:.||..::..|...||.|.|..  :...|||.....|| .:|.
Frog   515 LPNSCWIT--GWGFTEESGSLANILQKAEVPQISTEECQGNYEQTRIDKKILCAGYKRGKIDSCK 577

  Fly   209 GDSGGPL--VTHDGTKLVGVTNFGSVAGC-QSGAPAGFQRVTYHLDWIRDHTGI 259
            |||||||  |..:...|.|:|::|.  || :.|.|..:.||:...|||.:||.:
Frog   578 GDSGGPLACVVDEIWYLTGITSWGE--GCARPGKPGVYTRVSEFTDWIIEHTRV 629

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon66Cii	NP_648217.1	Tryp_SPc	39..253	CDD:214473	73/241 (30%)
Jon66Cii	NP_648217.1	Tryp_SPc	40..256	CDD:238113	74/243 (30%)
klkb1	XP_002934450.3	APPLE	21..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	290..373	CDD:128519
		Tryp_SPc	391..626	CDD:238113	74/243 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910