DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Jon66Cii and tmprss2.13

DIOPT Version :9

Sequence 1:	NP_648217.1	Gene:	Jon66Cii / 38953	FlyBaseID:	FBgn0035887	Length:	262	Species:	Drosophila melanogaster
Sequence 2:	XP_002943001.1	Gene:	tmprss2.13 / 100380113	XenbaseID:	XB-GENEPAGE-22065930	Length:	460	Species:	Xenopus tropicalis

Alignment Length:	250	Identity:	72/250 - (28%)
Similarity:	110/250 - (44%)	Gaps:	47/250 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 MQGRITNGYPAEEGKAPYTVGL----GFSGGWWCGGSIIAHDWVLTAEHCIGDADSVTVYFGATW 96
            :..||..|.||..|..|:...|    |.| .:.||||||...|::||.||:         :|:|
Frog   218 VDSRIVGGTPALVGDWPWQAQLLKLVGTS-TYLCGGSIITPYWIVTAAHCV---------YGST- 271

  Fly    97 RTNAQFTHWVGNGNFIKHSSA--------------------DIALIRI-PHVDFWHMVNKVELPS 140
            .|.:.|..:.|..:...:||:                    |:||::: ..:.|...:..|.||:
Frog   272 STPSIFKVFAGTLSIQSYSSSGRLVERALVHPNYTSNTQNYDVALLKLTAGLVFTTNLRPVCLPN 336

  Fly   141 YNDRYNDYNEWWAVACGWGGTYDGSPLPDYLQCVDLQIIHNSECSG---YYGSVGDNILCV-RTP 201
            ....::.....|  ..|||.|..|..:...|....:.:|.::.|:.   |.|::...::|. ...
Frog   337 VGMPWSGGQPCW--ISGWGTTSSGGSIATTLMAASVPLISSTTCNQAAVYGGAISPTMMCAGYLS 399

  Fly   202 DGKSTCGGDSGGPLVTHDGTK--LVGVTNFGSVAGC-QSGAPAGFQRVTYHLDWI 253
            .|..||.|||||||||...:.  |||.|::|  .|| .:..|..:..||..|:||
Frog   400 GGTDTCQGDSGGPLVTKTNSLWWLVGDTSWG--YGCATANKPGVYGNVTVFLEWI 452

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Jon66Cii	NP_648217.1	Tryp_SPc	39..253	CDD:214473	70/245 (29%)
Jon66Cii	NP_648217.1	Tryp_SPc	40..256	CDD:238113	70/245 (29%)
tmprss2.13	XP_002943001.1	SRCR_2	121..216	CDD:373897
tmprss2.13	XP_002943001.1	Tryp_SPc	222..452	CDD:238113	69/244 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000