Protein Alignment Culd and NETO1

DIOPT Version :9

• Sequence 1: NP_729364.1
• Gene: Culd / 38946
• FlyBaseID: FBgn0035880
• Length: 965
• Species: Drosophila melanogaster
• Sequence 2: NP_001188394.2
• Gene: NETO1 / 81832
• HGNCID: 13823
• Length: 533
• Species: Homo sapiens
• Alignment Length: 560
• Identity: 115/560 - (20%)
• Similarity: 201/560 - (35%)
• Gaps: 179/560 - (31%)

  Fly   186 GSPKQSI--------VGNGSTKSQPQVISTPYFPMAYPRD----------------------YGI 220
            |:.||:.        .|..:..::..:.::|.:|..||.|                      |.|
Human    26 GTEKQTTSETQKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSI 90

  Fly   221 EHILTCEADNCQVRLDFTDFQLGLTSTLEIFDSNGQMLDSYTGEHFRPPITVSSGKSLLLQ-FRG 284
            |....|:.|:.:||    |...|.:          .::..:.|:. .||:..|||:.|.:: |..
Human    91 EPSWECKFDHIEVR----DGPFGFS----------PIIGRFCGQQ-NPPVIKSSGRFLWIKFFAD 140

  Fly   285 NSATGVGFRAEVSFVSSKQLKD-ERLVPYTDCGGMVTGPGGAITMMNMIE--NATDVRLFDCIWI 346
            .....:||.|..:|......|| ..|.|...|...:.|..|.:..:.:::  .||.....||.|.
Human   141 GELESMGFSARYNFTPDPDFKDLGALKPLPACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWY 205

  Fly   347 IK--PGNNYMMMKTHISLRVDDFYGM-----AARSELTIRQGTTSDAVEIENVMWPNNGLSKESH 404
            |:  |       ::.|.||..| |.|     ..|:.:.:..|::|    :|::        |...
Human   206 IRAPP-------RSKIYLRFLD-YEMQNSNECKRNFVAVYDGSSS----VEDL--------KAKF 250

  Fly   405 VAPILNGYYIRL-RGVFGM-------SSKLAIVYSVFNYLNCYIGSEFLCGNNHCISIRLHCDGF 461
            .:.:.|...:|. .||..|       :|:..::::.|....|. |:.|.|.:|.||:..|.|:|.
Human   251 CSTVANDVMLRTGLGVIRMWADEGSRNSRFQMLFTSFQEPPCE-GNTFFCHSNMCINNTLVCNGL 314

  Fly   462 DHCGDGSDEPDSCEEDWAHLHHDRRWYSHKPNYYFPKIDQYPDLKTATGIF--IISTLG-IFGVL 523
            .:|....|| :.|:|                             |..|.:.  :.:|.| :.||.
Human   315 QNCVYPWDE-NHCKE-----------------------------KRKTSLLDQLTNTSGTVIGVT 349

  Fly   524 SGWMVILYRMGVRARHQRELQSHLQTISELLDRQDEDRT----PDEPPSYE--------APPDYE 576
            |..::||..:.|..:.::..:.::|.      :.|.|:|    ..|||.||        |..|:.
Human   350 SCIVIILIIISVIVQIKQPRKKYVQR------KSDFDQTVFQEVFEPPHYELCTLRGTGATADFA 408

  Fly   577 EVIKVGMQQELREPRRQRRARRAPPRDRSC---------SRAASNCTVQSVL------------- 619
            :|     ..:.....:.||:......|..|         ||:..:....|:|
Human   409 DV-----ADDFENYHKLRRSSSKCIHDHHCGSQLSSTKGSRSNLSTRDASILTEMPTQPGKPLIP 468

  Fly   620 PLHR----------------SCTLERDQEQPSTSAAAMTH 643
            |::|                :|.::..:|.|:||.....|
Human   469 PMNRRNILVMKHSYSQDAADACDIDEIEEVPTTSHRLSRH 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Culd	NP_729364.1	CUB	200..298	CDD:238001	25/120 (21%)
		LDLa	442..472	CDD:238060	11/29 (38%)
NETO1	NP_001188394.2	CUB	51..154	CDD:238001	25/117 (21%)
		CUB	<200..286	CDD:238001	22/105 (21%)
		LDLa	291..326	CDD:381805	13/36 (36%)
		PDZ-binding	531..533

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000