DRSC/TRiP Functional Genomics Resources

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Protein Alignment Culd and LRP8

DIOPT Version :10

Sequence 1:NP_729364.1 Gene:Culd / 38946 FlyBaseID:FBgn0035880 Length:965 Species:Drosophila melanogaster
Sequence 2:NP_004622.2 Gene:LRP8 / 7804 HGNCID:6700 Length:963 Species:Homo sapiens


Alignment Length:32 Identity:17/32 - (53%)
Similarity:21/32 - (65%) Gaps:0/32 - (0%)


- Green bases have known domain annotations that are detailed below.


  Fly   442 SEFLCGNNHCISIRLHCDGFDHCGDGSDEPDS 473
            |:|.|.|.|||..|..|||.:.|.|||||.::
Human    89 SDFTCDNGHCIHERWKCDGEEECPDGSDESEA 120

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CuldNP_729364.1 CUB 200..298 CDD:238001
LDLa 442..472 CDD:238060 17/29 (59%)
LRP8NP_004622.2 LDLa 47..81 CDD:238060
LDLa 85..117 CDD:197566 15/27 (56%)
LDLa 127..163 CDD:238060
LDLa 206..240 CDD:197566
Ldl_recept_a 262..294 CDD:395011
Ldl_recept_a 298..333 CDD:395011
FXa_inhibition 340..374 CDD:464251
EGF_CA 376..406 CDD:214542
LY 445..480 CDD:214531
LDL-receptor class B 1 462..508
LY 489..531 CDD:214531
LDL-receptor class B 2 509..551
LDL-receptor class B 3 552..595
Ldl_recept_b 552..592 CDD:459654
LY 576..618 CDD:214531
LDL-receptor class B 4 596..639
Ldl_recept_b 639..679 CDD:459654
LDL-receptor class B 5 640..681
FXa_inhibition 697..734 CDD:464251
Clustered O-linked oligosaccharides 740..798
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 754..815
Blue background indicates that the domain is not in the aligned region.

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