Protein Alignment Culd and arr

DIOPT Version :9

• Sequence 1: NP_729364.1
• Gene: Culd / 38946
• FlyBaseID: FBgn0035880
• Length: 965
• Species: Drosophila melanogaster
• Sequence 2: NP_524737.2
• Gene: arr / 44279
• FlyBaseID: FBgn0000119
• Length: 1678
• Species: Drosophila melanogaster
• Alignment Length: 1045
• Identity: 186/1045 - (17%)
• Similarity: 298/1045 - (28%)
• Gaps: 444/1045 - (42%)

  Fly    19 LCWPGEAYPASSSYRDLDICNHWDGRRHFLELGSPAGEVHARNVTTTAYRSSPLVFKNDAVAGDV 83
            |.|..::.||.....|      |||::..:.:||...|.:|    .:.|:.  .|:.:|...||:
  Fly   883 LYWATQSRPAKIESAD------WDGKKRQILVGSDMDEPYA----VSLYQD--YVYWSDWNTGDI 935

  Fly    84 WYQCSLELV--TCAE--CVIRVAFTYA------NFSKSCG------NTGGKSSMCPCE------- 125
                  |.|  |..:  .::....||.      |..:..|      |.||.|.:|..:
  Fly   936 ------ERVHKTTGQNRSLVHSGMTYITSLLVFNDKRQTGVNPCKVNNGGCSHLCLAQPGRRGMT 994

  Fly   126 -----HIQFSE------PPYDSTISGQEFCGDGKVFRSKTRTLQLKFFYRASNA----------H 169
                 |.|.::      ||.:..|..|..| .|::..:.|....:.......|.          |
  Fly   995 CACPTHYQLAKDGVSCIPPRNYIIFSQRNC-FGRLLPNTTDCPNIPLPVSGKNIRAVDYDPITHH 1058

  Fly   170 VFSLQYFSERNVRIVSGSPKQSIVGNGSTKSQPQVISTPYFPMAYPRDYGIEHI-----LTCEAD 229
            ::.::..|....|.::...|.|::.|.                ..|.|..|:.|     .||...
  Fly  1059 IYWIEGRSHSIKRSLANGTKVSLLANS----------------GQPFDLAIDIIGRLLFWTCSQS 1107

  Fly   230 NCQVRLDFTDFQLGLTSTLEIFDSNGQMLDSYTGEHFRP-PITVSSGKSLLL------------- 280
            |   .::.|.|   |..::.:.|         ||:..:| .|.|.:.|.||.
  Fly  1108 N---SINVTSF---LGESVGVID---------TGDSEKPRNIAVHAMKRLLFWTDVGSHQAIIRA 1157

  Fly   281 QFRGNSATGVGFRAE-VSFVSSKQLKDERLVPYTDCGGMVTGPGGAITMMNMIENATDVRLFDCI 344
            :..||....:.::.| |:.::..|..|                        ||..|...|: |.|
  Fly  1158 RVDGNERVELAYKLEGVTALALDQQSD------------------------MIYYAHGKRI-DAI 1197

  Fly   345 WIIKPGNNYMMMKTHISLRVDDFYGMAAR-------------SELTIRQGTTS-------DAVEI 389
            .|  .|.|   .||.:|:.:.....:||.             ..:|:.....|       ...:|
  Fly  1198 DI--NGKN---KKTLVSMHISQVINIAALGGFVYWLDDKTGVERITVNGERRSAELQRLPQITDI 1257

  Fly   390 ENVMWPN----------NGLSKESHVAPILNGYYI-RLRGVFGMSSKLAIVYSVFN--------- 434
            ..|..|:          :..:|.||:. |.:|..| |.|.|......|.::....|
  Fly  1258 RAVWTPDPKVLRNHTCMHSRTKCSHIC-IASGEGIARTRDVCSCPKHLMLLEDKENCGAFPACGP 1321

  Fly   435 -YLNC--------------------------------YIG------SEFLCGNNHCISIRLHCDG 460
             :..|                                .:|      .:|.|.:..||...|.|||
  Fly  1322 DHFTCAAPVSGISDVNKDCIPASWRCDGQKDCPDKSDEVGCPTCRADQFSCQSGECIDKSLVCDG 1386

  Fly   461 FDHCGDGSDEPDSCEEDWAHLHHDRRWYSHKPNYYFPKIDQYPDLKTATGIFIISTLGIFGVL-- 523
            ..:|.:|.||.|.|:               :|..:     |.|          |:.|.|...|
  Fly  1387 TTNCANGHDEADCCK---------------RPGEF-----QCP----------INKLCISAALLC 1421

  Fly   524 SGWMVILYRMGVRARHQRELQSHLQTISELLDRQDEDRTPDEPPSYEAPPDYEEVIKVGMQQELR 588
            .||                        ....|..||..                  .:.:|:
  Fly  1422 DGW------------------------ENCADGADESS------------------DICLQR--- 1441

  Fly   589 EPRRQRRARRAPPRDRSCSRA------ASNCTVQSVLPLHRSC--TLERDQEQPSTSAAAMTHAV 645
                    |.||..|:   ||      |:..|:.|::.|.:.|  .:.:.:.:|...
  Fly  1442 --------RMAPATDK---RAFMILIGATMITIFSIVYLLQFCRTRIGKSRTEPKDD-------- 1487

  Fly   646 AATDTTEDAEHVQTMAQRMLLATAICGTAGTSLPAAKESGQRVQ---SVGISTSPSSLSAGGELP 707
            .|||...                          |:.....|||.   ||..:...|:|::...:.
  Fly  1488 QATDPLS--------------------------PSTLSKSQRVSKIASVADAVRMSTLNSRNSMN 1526

  Fly   708 -------TAGGSATTPGSTADECTQGGDSLSISLTLGLPSTTAESPVTTDQNQLQKQSPEQTISN 765
                   |...|:||.||:               .:..|.....||.|..:...
  Fly  1527 SYDRNHITGASSSTTNGSS---------------MVAYPINPPPSPATRSRRPY----------- 1565

  Fly   766 CTEHTFLKRSWLVVQQVPP------------GRGYRVR---------RLRHTFSSPEA-----FT 804
                    |.:.::.|.||            ...|..:         ..:|:.||..|     :.
  Fly  1566 --------RHYKIINQPPPPTPCSTDICDESDSNYTSKSNSNNSNGGATKHSSSSAAACLQYGYD 1622

  Fly   805 SDELHLPYPDFLSYGTNLPHERSSSNFGSELSRDPSSYSVGKRARLTPEDTSGSETITQEMEQSN 869
            |:    |||         |.....|::.|::...|.|       ...|..:|.|.|....:....
  Fly  1623 SE----PYP---------PPPTPRSHYHSDVRIVPES-------SCPPSPSSRSSTYFSPLPPPP 1667

  Fly   870 QTLQS 874
            ..:||
  Fly  1668 SPVQS 1672

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Culd	NP_729364.1	CUB	200..298	CDD:238001	23/117 (20%)
		LDLa	442..472	CDD:238060	12/29 (41%)
arr	NP_524737.2	LY	162..201	CDD:214531
		NHL	168..503	CDD:302697
		NHL repeat	172..237	CDD:271320
		LY	252..293	CDD:214531
		NHL repeat	261..298	CDD:271320
		NHL repeat	303..339	CDD:271320
		NHL repeat	341..419	CDD:271320
		NHL repeat	428..476	CDD:271320
		LY	472..511	CDD:214531
		NHL repeat	477..503	CDD:271320
		Ldl_recept_b	534..573	CDD:278487
		LY	558..599	CDD:214531
		LY	600..641	CDD:214531
		FXa_inhibition	668..703	CDD:291342
		LY	739..773	CDD:214531
		LY	776..818	CDD:214531
		LY	819..860	CDD:214531
		FXa_inhibition	973..1010	CDD:291342	7/36 (19%)
		LY	1122..1164	CDD:214531	11/50 (22%)
		FXa_inhibition	1273..1313	CDD:291342	10/40 (25%)
		LDLa	1319..1362	CDD:238060	1/42 (2%)
		LDLa	1365..1399	CDD:238060	12/33 (36%)
		LDLa	1399..1433	CDD:197566	11/87 (13%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1215
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900