DRSC/TRiP Functional Genomics Resources

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Protein Alignment Culd and LRP4

DIOPT Version :9

Sequence 1:NP_729364.1 Gene:Culd / 38946 FlyBaseID:FBgn0035880 Length:965 Species:Drosophila melanogaster
Sequence 2:NP_002325.2 Gene:LRP4 / 4038 HGNCID:6696 Length:1905 Species:Homo sapiens


Alignment Length:50 Identity:21/50 - (42%)
Similarity:22/50 - (44%) Gaps:14/50 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   443 EFLCGNNHCISIRLHCDGFDHCGDGSDEPDSCEEDWAHLHHDRRWYSHKP 492
            ||.|....||....||||.|.|||.|||.| |.             ||:|
Human   195 EFQCAYGRCILDIYHCDGDDDCGDWSDESD-CS-------------SHQP 230

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CuldNP_729364.1 CUB 200..298 CDD:238001
LDLa 442..472 CDD:238060 16/28 (57%)
LRP4NP_002325.2 LDLa 27..66 CDD:238060
Ldl_recept_a 70..105 CDD:278486
LDLa 110..142 CDD:238060
LDLa 148..182 CDD:238060
LDLa 231..265 CDD:238060 20/49 (41%)
LDLa 270..304 CDD:238060
LDLa 311..343 CDD:197566
FXa_inhibition 358..393 CDD:291342
EGF_CA 395..434 CDD:214542
NHL <471..622 CDD:302697
NHL repeat 471..507 CDD:271320
LDL-receptor class B 1 480..522
LY 505..545 CDD:214531
NHL repeat 510..550 CDD:271320
LDL-receptor class B 2 523..565
NHL repeat 555..589 CDD:271320
LDL-receptor class B 3 566..609
LY 590..632 CDD:214531
NHL repeat 598..622 CDD:271320
LDL-receptor class B 4 610..652
LY 633..673 CDD:214531
LDL-receptor class B 5 653..693
FXa_inhibition 702..>729 CDD:291342
LY 766..806 CDD:214531
LDL-receptor class B 6 785..827
LY 808..850 CDD:214531
LDL-receptor class B 7 828..870
LDL-receptor class B 8 871..914
Ldl_recept_b 871..911 CDD:278487
LY 895..937 CDD:214531
LDL-receptor class B 9 915..956
LY 938..979 CDD:214531
LDL-receptor class B 10 957..998
FXa_inhibition 1006..1043 CDD:291342
NHL <1085..1277 CDD:302697
NHL repeat 1085..1123 CDD:271320
LDL-receptor class B 11 1093..1135
NHL repeat 1128..1161 CDD:271320
LDL-receptor class B 12 1136..1178
NHL repeat 1166..1203 CDD:271320
LDL-receptor class B 13 1179..1222
Ldl_recept_b 1179..1219 CDD:278487
NHL repeat 1212..1244 CDD:271320
LDL-receptor class B 14 1223..1263
NHL repeat 1253..1277 CDD:271320
LDL-receptor class B 15 1264..1306
FXa_inhibition 1313..1348 CDD:291342
LY 1379..1418 CDD:214531
LDL-receptor class B 16 1397..1439
LY 1420..1460 CDD:214531
LDL-receptor class B 17 1440..1482
LDL-receptor class B 18 1483..1526
Ldl_recept_b 1483..1523 CDD:278487
LY 1507..1547 CDD:214531
LDL-receptor class B 19 1527..1568
LY 1549..1589 CDD:214531
LDL-receptor class B 20 1569..1610
FXa_inhibition 1617..>1641 CDD:291342
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1659..1686
Endocytosis signal. /evidence=ECO:0000255 1766..1769
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1852..1905
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1215
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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