DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Culd and egg-1

DIOPT Version :9

Sequence 1:NP_729364.1 Gene:Culd / 38946 FlyBaseID:FBgn0035880 Length:965 Species:Drosophila melanogaster
Sequence 2:NP_498237.2 Gene:egg-1 / 175804 WormBaseID:WBGene00015083 Length:551 Species:Caenorhabditis elegans


Alignment Length:433 Identity:80/433 - (18%)
Similarity:126/433 - (29%) Gaps:176/433 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly   434 NYLNCYIGS------------EFLC-GNNHCISIRLHCDGFDHCGDGSDEPD--SCEEDWAHLHH 483
            |..||..||            :|.| |:|.|:.:...|||.:.|.|.|||.:  .|:.:      
 Worm   199 NVENCPDGSDEAVCKSSCSKDQFKCPGSNACLPLSAKCDGINDCADASDEKNCSKCQNN------ 257

  Fly   484 DRRWYSHKPNYYFPKIDQYPDLKTATGIFIISTLGIFGVLSGWMVILYRMGVRARHQRELQSHLQ 548
                 :||..                                      :..::|.|.      ..
 Worm   258 -----AHKCG--------------------------------------KQCIKASHV------CD 273

  Fly   549 TISELLDRQDEDRTPDEPPSYEAPPDYEEVIKVGMQQELREPRRQRRARRAPPRDRSCS------ 607
            .:::..|..||.:...:..|             |..:.|.:........:.....:.|:      
 Worm   274 GVAQCADGSDEQQCDCQRCS-------------GTDKALCDDGTCIMRTQVCDGKKDCTDGMDEE 325

  Fly   608 RAASNCTVQSVLPLHRSCTLERDQEQPSTSAAAMTHAVAATDTTEDAEH---------------- 656
            ....:||::|..|..:..|.. |.:|       .|.|.|.:.:.|..:|                
 Worm   326 DCPGSCTIESFSPKLKMVTCS-DGKQ-------YTEAEACSGSFESCDHDCPNSKCHPKLAFTCP 382

  Fly   657 VQTMAQRMLLA--------------------TAI--CGTA-GTSLPA---AKESGQRVQSV---- 691
            ....|::|.::                    |.|  ||.| .|....   ..:|.:|...|    
 Worm   383 ASKEARKMCISRRKVCDGTPDCDDGADEINCTPIKECGIAKNTQFKCDHKCLDSSRRCDGVWDCE 447

  Fly   692 ------GISTSPSSLSAGGELPTAGGSATTPGST----ADECTQGGDSLSISL--TLGLPSTTAE 744
                  |....||     |.:..|......|..|    ..:|:.|.|.|..|.  .||:.|.|. 
 Worm   448 DKSDEKGCDKCPS-----GTIKCAADKKCLPAFTRCNGVADCSDGSDELKCSCQECLGVHSNTY- 506

  Fly   745 SPVTTDQNQLQKQ----SPEQTISNCTEHT--------FLKRS 775
              :..:.|:..|:    ||.....|.| :|        |||:|
 Worm   507 --MCNESNRCLKRDEVCSPYSMCPNAT-YTDKAFCAALFLKKS 546

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CuldNP_729364.1 CUB 200..298 CDD:238001
LDLa 442..472 CDD:238060 14/42 (33%)
egg-1NP_498237.2 LDLa 123..159 CDD:238060
LDLa 216..251 CDD:238060 13/34 (38%)
LDLa 254..287 CDD:238060 8/87 (9%)
LDLa 300..327 CDD:238060 1/26 (4%)
LDLa <391..413 CDD:238060 0/21 (0%)
LDLa 425..455 CDD:238060 4/29 (14%)
LDLa 458..493 CDD:238060 10/39 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1215
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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