| Sequence 1: | NP_729364.1 | Gene: | Culd / 38946 | FlyBaseID: | FBgn0035880 | Length: | 965 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | XP_036011543.1 | Gene: | Lrp1 / 16971 | MGIID: | 96828 | Length: | 4562 | Species: | Mus musculus |
| Alignment Length: | 907 | Identity: | 175/907 - (19%) |
|---|---|---|---|
| Similarity: | 276/907 - (30%) | Gaps: | 309/907 - (34%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 40 HWDGRRHFLELGSPAGEVHARNVTTTAYRSSPL------------VFKNDAVAGDVWYQCSLELV 92
Fly 93 TCAE-CVIRVAFTYANFSKSCGNTGGKSSMCPCEHIQFSEPPYDSTISGQEFCG-----DGKVFR 151
Fly 152 S---------------------KTRTLQLKFFYRA------------SNAHVFSLQYFSERNVRI 183
Fly 184 VSGSPKQSIVGN----------------------GSTKSQPQVISTPYFPMAYPRD-----YGIE 221
Fly 222 HILTCEADNCQVRLDFTDFQLGLTSTLEIFDSNGQMLDSYTGEHFRPPI--TVSSGKSLLL---- 280
Fly 281 QFRGNSATGVGFRAEVSFVSSKQ-----------------LKDERLVPYTDCGGMVTGPGGAITM 328
Fly 329 MNMIENATDVRLFDCIWI---IKPGNNYMMMKTHISLRVDDFYGMAARSELTIRQGTTSDAVEIE 390
Fly 391 NVMWPNNG------LSKESHVAPILNGYYIRLRGVFGMSSKLAIVYSVFNYLNCYIGSEFLCGNN 449
Fly 450 HCISIRLHCDGFDHCGDGSDEPDS------CEEDWAHLHHDR-----RWYSHKPNYYFPKIDQYP 503
Fly 504 DLKTATGIFIISTLGIFGVLSGWMVILYRMGVRARHQRELQSHLQTISELLDRQDEDRTPDEPPS 568
Fly 569 YEAPPDYEEVIKVGMQQELREPRRQRRARRAP-------------PRDRSC-----SRAASN--- 612
Fly 613 CTVQSVLPLHRSCTLERDQEQPSTSAAAMTHA-VAATDTTEDAEHVQTMAQRMLL-ATAICGTAG 675
Fly 676 TSLPAAKESGQRVQSVGISTSPSSLSAGGELPTAGGSATTPGSTADECTQGGDSLSISLTLG-LP 739
Fly 740 STTAESPVTTDQNQL-----------------QKQSPEQTISNCTEHTF--------LKRSW 776 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Culd | NP_729364.1 | CUB | 200..298 | CDD:238001 | 20/108 (19%) |
| LDLa | 442..472 | CDD:238060 | 17/29 (59%) | ||
| Lrp1 | XP_036011543.1 | LDLa | 27..60 | CDD:197566 | |
| LDLa | 72..105 | CDD:197566 | |||
| FXa_inhibition | 120..149 | CDD:405372 | |||
| FXa_inhibition | 159..189 | CDD:405372 | |||
| LY | 276..315 | CDD:214531 | |||
| LY | 317..359 | CDD:214531 | |||
| LY | 362..402 | CDD:214531 | |||
| FXa_inhibition | 487..520 | CDD:405372 | |||
| LY | 552..594 | CDD:214531 | |||
| LY | 595..634 | CDD:214531 | |||
| LY | 641..690 | CDD:214531 | |||
| LY | <701..734 | CDD:214531 | |||
| FXa_inhibition | 808..843 | CDD:405372 | |||
| LDLa | 854..886 | CDD:197566 | |||
| LDLa | 896..929 | CDD:238060 | |||
| LDLa | 936..968 | CDD:197566 | |||
| LDLa | 979..1012 | CDD:238060 | |||
| LDLa | 1033..1066 | CDD:238060 | |||
| LDLa | 1080..1115 | CDD:238060 | |||
| LDLa | 1122..1158 | CDD:238060 | |||
| LDLa | 1163..1196 | CDD:238060 | |||
| FXa_inhibition | 1203..1239 | CDD:405372 | |||
| LY | 1354..1394 | CDD:214531 | |||
| LY | 1398..1441 | CDD:214531 | |||
| LY | 1442..1486 | CDD:214531 | |||
| LY | 1631..1667 | CDD:214531 | |||
| LY | 1668..1711 | CDD:214531 | |||
| LY | 1715..1752 | CDD:214531 | |||
| LY | 1752..1793 | CDD:214531 | |||
| FXa_inhibition | 1868..1904 | CDD:405372 | |||
| LY | 1934..1974 | CDD:214531 | |||
| LY | 1977..2017 | CDD:214531 | |||
| LY | 2018..2061 | CDD:214531 | |||
| LY | 2063..2105 | CDD:214531 | |||
| FXa_inhibition | 2177..2212 | CDD:405372 | 10/53 (19%) | ||
| YvrE | 2271..2481 | CDD:225921 | 46/264 (17%) | ||
| Ldl_recept_b | 2362..2403 | CDD:395012 | 7/63 (11%) | ||
| LY | 2388..2429 | CDD:214531 | 5/40 (13%) | ||
| FXa_inhibition | 2500..2532 | CDD:405372 | 8/32 (25%) | ||
| LDLa | 2545..2575 | CDD:238060 | 16/29 (55%) | ||
| LDLa | 2584..2618 | CDD:238060 | 4/34 (12%) | ||
| LDLa | 2623..2657 | CDD:238060 | 10/58 (17%) | ||
| LDLa | <2684..2706 | CDD:238060 | 3/21 (14%) | ||
| LDLa | 2714..2748 | CDD:238060 | 7/37 (19%) | ||
| LDLa | 2752..2783 | CDD:197566 | 4/39 (10%) | ||
| LDLa | 2791..2824 | CDD:197566 | 9/34 (26%) | ||
| LDLa | 2835..2867 | CDD:197566 | 4/31 (13%) | ||
| LDLa | 2875..2908 | CDD:197566 | 4/20 (20%) | ||
| LDLa | 2925..2957 | CDD:238060 | |||
| cEGF | 2980..3003 | CDD:403760 | |||
| EGF_CA | 3000..>3029 | CDD:214542 | |||
| LY | 3067..3111 | CDD:214531 | |||
| LY | 3112..3154 | CDD:214531 | |||
| LY | 3156..3198 | CDD:214531 | |||
| LY | 3200..3241 | CDD:214531 | |||
| LY | 3242..3282 | CDD:214531 | |||
| FXa_inhibition | 3312..3348 | CDD:405372 | |||
| LDLa | 3352..3383 | CDD:238060 | |||
| LDLa | 3392..3426 | CDD:238060 | |||
| LDLa | 3431..3466 | CDD:238060 | |||
| LDLa | 3470..3503 | CDD:197566 | |||
| LDLa | 3511..3544 | CDD:197566 | |||
| LDLa | 3554..3588 | CDD:238060 | |||
| LDLa | 3593..3627 | CDD:238060 | |||
| LDLa | 3631..3665 | CDD:238060 | |||
| LDLa | 3671..3703 | CDD:197566 | |||
| LDLa | 3713..3749 | CDD:238060 | |||
| LDLa | 3764..3794 | CDD:238060 | |||
| LY | 3973..4010 | CDD:214531 | |||
| Ldl_recept_b | 4031..4071 | CDD:395012 | |||
| LY | 4055..4096 | CDD:214531 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG1215 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.900 | |||||