DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment GAPcenA and MSB4

DIOPT Version :9

Sequence 1:NP_001097549.1 Gene:GAPcenA / 38945 FlyBaseID:FBgn0035879 Length:1194 Species:Drosophila melanogaster
Sequence 2:NP_014529.1 Gene:MSB4 / 854037 SGDID:S000005472 Length:492 Species:Saccharomyces cerevisiae


Alignment Length:464 Identity:103/464 - (22%)
Similarity:178/464 - (38%) Gaps:113/464 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   596 EDDCPSDYSSDGDEPLLSGTGEVSKD-------------------------CSQDTLDEW----- 630
            :||...|.||..:...:..|.|:.|.                         .||:..|:|     
Yeast    40 DDDDEGDDSSTVERKEILTTRELEKAKAFTSLIMADPENFDRYGFSKKGYFISQEEYDKWWTEYN 104

  Fly   631 ---DPILREWDS-----------------EKRPKNLAPLVRLGVPEALREKIWQKLANVEGRMEM 675
               :...::|::                 ..|...|:..||.|:|...|...|...|..:.:::.
Yeast   105 RYTERRKKKWENFLLKNKIELHNDNPLVYPARTDELSKFVRKGIPAEWRGNAWWYFAGGQRQLDA 169

  Fly   676 N----DKYKILITKETKCE---------TVIQRDIHRTFPAHKCF-KEIGGSGQDALF----KVS 722
            |    |:.|      :.|.         ..|:||::||||.:..| ||...:|:.|:.    :|.
Yeast   170 NVGVYDRLK------SDCREGAVSGKDMEAIERDLYRTFPDNIHFHKESFQNGEPAIIRSLRRVL 228

  Fly   723 KAYAVHDSEVGYCQGLSFIAASLLLHMPEEDAFCVLVALMYDYGLRDLYKAGFEVLYLRLYQLER 787
            .|::|:|..:||||.::|:...|||.|.||.||.:||.:...| |..:|::..|...:....|..
Yeast   229 MAFSVYDKTIGYCQSMNFLVGLLLLFMEEEKAFWMLVIITGKY-LPGVYESDLEGANVDQGVLVL 292

  Fly   788 LIKDQLPKLHEHFTA----------------------CGIET-HMYASQWFLTLYTARFPLCFVF 829
            .||:.||::..|..:                      |.:.| .:..:.||::.:....|:....
Yeast   293 CIKEYLPEIWSHIESSYMNGNGSTDQISGPASGEEYLCRLPTLTLCTASWFMSCFVGVVPIETTL 357

  Fly   830 HVLDVFLLDGLPVLFQVAVTLLSICESDLRQLDFEGILKYFRVTLPKKCRSSSQARKVMKQACER 894
            .:.|....:....||:||:.:|.:.||:..:...:   |.||.........|:.:....|: .:.
Yeast   358 RIWDCLFYEESHFLFKVALGILKLSESEFLESKSQ---KLFRQYSSYTFGGSNDSDSTFKR-LKN 418

  Fly   895 KIKKLKQYEEEFLLKKQH-KERLEKEAQIYE----------NRFGEERRKMQAEIDALNKQLTSA 948
            |||..::.:.|.|...|: .:||.....|:|          |...:|:.....|..|:.:....|
Yeast   419 KIKTQEEADMEILQVIQNFPKRLLNPNDIFEKVLMKKKVALNGITQEKIDRGREYVAMARNRQRA 483

  Fly   949 KERAVEKEK 957
            ..|..|:.|
Yeast   484 SSRPKERRK 492

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GAPcenANP_001097549.1 PTB_Rab6GAP 204..332 CDD:269922
DUF3694 429..523 CDD:289256
TBC 650..858 CDD:214540 65/248 (26%)
Phage_Gp23 <914..991 CDD:287621 12/54 (22%)
MSB4NP_014529.1 COG5210 <53..461 CDD:227535 90/418 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5210
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

Return to query results.
Submit another query.