Protein Alignment GAPcenA and GRTP1

DIOPT Version :10

• Sequence 1: NP_001097549.1
• Gene: GAPcenA / 38945
• FlyBaseID: FBgn0035879
• Length: 1194
• Species: Drosophila melanogaster
• Sequence 2: NP_001273661.1
• Gene: GRTP1 / 79774
• HGNCID: 20310
• Length: 344
• Species: Homo sapiens
• Alignment Length: 281
• Identity: 81/281 - (28%)
• Similarity: 132/281 - (46%)
• Gaps: 33/281 - (11%)

  Fly   629 EWDPILREWDSEKRPKNLAPLVRLGVPEALREKIWQKLANVEGRMEMNDKYKILI---TKETKCE 690
            :|..:| :.....|.:.:...||.|||...|.::|..|:..:.:|:.|..|...:   .:..:.|
Human    45 KWSRLL-QGGGVPRSRTVKRYVRKGVPLEHRARVWMVLSGAQAQMDQNPGYYHQLLQGERNPRLE 108

  Fly   691 TVIQRDIHRTFPAHKCF-KEIGGSGQDALFKVSKAYAVHDSEVGYCQGLSFIAASL-LLHMPEED 753
            ..|:.|::||||.:..| |......|..|:.|..||..|:..||||||::|||..| |:...||:
Human   109 DAIRTDLNRTFPDNVKFRKTTDPCLQRTLYNVLLAYGHHNQGVGYCQGMNFIAGYLILITNNEEE 173

  Fly   754 AFCVLVALMYDYG--LRDLYKAGFEVLYLRLYQ--LERLIKDQLPKLHEHFTACGIETHMYASQW 814
            :|.:|.||:   |  |.|.|...  :|.|:..|  |..|::.:||.:.......|:...:..|:|
Human   174 SFWLLDALV---GRILPDYYSPA--MLGLKTDQEVLGELVRAKLPAVGALMERLGVLWTLLVSRW 233

  Fly   815 FLTLYTARFPLCFVFHVLDVFLLDGLPVLFQVAVTLLSICESDLRQLDFEGILKYFRVTLPKKCR 879
            |:.|:....|:..|..:.|....:|..::|:||:||:    ...::|..|.      .::|..|.
Human   234 FICLFVDILPVETVLRIWDCLFNEGSKIIFRVALTLI----KQHQELILEA------TSVPDICD 288

  Fly   880 SSSQARK---VMK-----QAC 892
            ...|..|   ||:     |.|
Human   289 KFKQITKGSFVMECHTFMQVC 309

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GAPcenA	NP_001097549.1	PTB_Rab6GAP	204..332	CDD:269922
		DUF3694	377..523	CDD:463599
		TBC	650..858	CDD:214540	68/216 (31%)
		SMC_prok_B	<876..>1087	CDD:274008	7/25 (28%)
		TPH	<883..>977	CDD:464007	6/18 (33%)
GRTP1	NP_001273661.1	TBC	65..278	CDD:214540	69/221 (31%)