DRSC/TRiP Functional Genomics Resources

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Protein Alignment GAPcenA and si:ch211-266k8.4

DIOPT Version :9

Sequence 1:NP_001097549.1 Gene:GAPcenA / 38945 FlyBaseID:FBgn0035879 Length:1194 Species:Drosophila melanogaster
Sequence 2:XP_687788.5 Gene:si:ch211-266k8.4 / 559362 ZFINID:ZDB-GENE-131121-469 Length:617 Species:Danio rerio


Alignment Length:612 Identity:129/612 - (21%)
Similarity:247/612 - (40%) Gaps:148/612 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly   572 SSSLLKMGMNNLSRIVRSSSIA--------------SIEDDCPSDYSSDGDEPLLSGTGEVSKDC 622
            |||......|...|  ||||:.              .::..| .|||.....|:     :|.:.|
Zfish     7 SSSSSGKSCNKPRR--RSSSVGFDEFGFAFSKKRDKKLQQRC-HDYSYPQPNPV-----KVKELC 63

  Fly   623 SQDTLDEWDP---ILREWDSEKRPKNLAPLVRLGVPEALREKIWQKLANVEG------------- 671
              :.|..|:.   |.|        ..:...:|:|:|.|:|.::|:.|.|::.             
Zfish    64 --EFLSYWNGSSFICR--------SQIERFIRIGIPPAIRGRVWRCLLNIDSLRATSCFNYEDCQ 118

  Fly   672 ---RMEMND----KYKILITKETKCET---------------------VIQRDIHRTFPAHKCFK 708
               |..:.|    :|.|:.:.::..:|                     .|..|:.|:||.|:.. 
Zfish   119 SEIRRPLVDLGVSEYSIISSIDSLVDTENEISSGQASSPQVADLTLFKQIALDLQRSFPTHRTL- 182

  Fly   709 EIGG-----SGQDALFKVSKAYAVHDSEVGYCQGLSFIAASLLLHMPEEDAFCVLVALM----YD 764
             :|.     .||..||:|..|:|.::..:||.||:|:|||.||:.:.||:||..||||:    | 
Zfish   183 -MGDRPEAIEGQAKLFRVLSAFARYNPLIGYVQGMSYIAAVLLMILSEEEAFWALVALLEKPKY- 245

  Fly   765 YGLRDLYKAGFEVLYLRLYQLERLIKDQLPKLHEHFTACGIETHMYASQWFLTLYTARFPLCF-- 827
              |.:|:.:..:.:..:.....:|:|.:.|.|.:|....|:....:..||||||:|: .| |:  
Zfish   246 --LSELFDSSMKKIQHQALVFHQLLKHRKPLLFQHLETLGVSCVHFIMQWFLTLFTS-LP-CWDS 306

  Fly   828 VFHVLDVFLLDGLPVLFQVAVTLLSICESDLRQLDFEG-----ILK------YFRVTLPKKCRSS 881
            |..:.|:.:|.||..:|:..:|::.:.||.:..:..|.     :|:      :.||.:|....:.
Zfish   307 VLAIWDLIMLHGLQAVFRTGLTIILLLESRIMNMTEEATVLPLLLRVPIDICHHRVLIPALWSTD 371

  Fly   882 SQARKVMKQACERKIKKLKQYEEEFLLKKQHKERLEKE-----------AQIYENRFGEERRKMQ 935
            .|         |.:|..:.....|.|...|.:|:..||           .|:::.:..:|..|.:
Zfish   372 LQ---------EWEINCMNSLVLEELDSTQDEEKANKENTKISTASFSDGQLHDEKPLQETAKKE 427

  Fly   936 AEIDALNK---QLTSAKERAVEKEKKHTGIIQEYKQIIQRQEQDMNTLSETLGKVMHMVSNCQDC 997
            |...:...   :|....:..:.|..|::          ...:......|...|::....::....
Zfish   428 ASASSSKSVFTRLLKVAQHFILKSGKYS----------SAAKSSPTKRSPAPGRLAKTRTSSHFT 482

  Fly   998 QQQIDAGNDNAKSDDGKNRG--QTDAMRNANEHPLGPLDPLNAASQRIRELELELAQAKLAQVEA 1060
            |.|:.....:::.....::|  :.:.:.:.|.......|..::::.|:|       ...:.:| |
Zfish   483 QTQVRGRRSSSRRSQSSSQGGVRKEKLPSQNSDGGAAEDSSDSSAWRVR-------SGPVGKV-A 539

  Fly  1061 ECKNQDLNHQLSNTLSELQTNRNSWQP 1087
            ..:::|.:.:.|:..|..:.:|:...|
Zfish   540 RRRSRDQSRRGSSFHSRSRRSRSQQTP 566

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GAPcenANP_001097549.1 PTB_Rab6GAP 204..332 CDD:269922
DUF3694 429..523 CDD:289256
TBC 650..858 CDD:214540 72/259 (28%)
Phage_Gp23 <914..991 CDD:287621 12/90 (13%)
si:ch211-266k8.4XP_687788.5 RabGAP-TBC 166..338 CDD:278964 59/178 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5210
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.810

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