Protein Alignment GAPcenA and Sgsm1

DIOPT Version :9

• Sequence 1: NP_001097549.1
• Gene: GAPcenA / 38945
• FlyBaseID: FBgn0035879
• Length: 1194
• Species: Drosophila melanogaster
• Sequence 2: XP_006535185.1
• Gene: Sgsm1 / 52850
• MGIID: 107320
• Length: 1148
• Species: Mus musculus
• Alignment Length: 618
• Identity: 121/618 - (19%)
• Similarity: 215/618 - (34%)
• Gaps: 134/618 - (21%)

  Fly   276 ILYYRGPVDTVENGCFAFTWLHGDALFQCHVFRCHIPEAVNQVSACFQKAFQTYPPSMSCSLNSA 340
            ::||.|....:....:.|...|    :|..:......|...|:.||:.   ||....:.|
Mouse   612 LIYYGGVQPEIRRAVWPFLLGH----YQFGMTEMERKEVDEQIHACYA---QTMSEWLGC----- 664

  Fly   341 VDMANSVTSDVSGNPLNTAGYEFIVSLEIRERVAKNSYAAVPRDRGCFKLRANTDKEVCITVKQT 405
                                 |.||    |:|..::..||:.:               |.:....
Mouse   665 ---------------------EAIV----RQRERESHAAALAK---------------CSSGASL 689

  Fly   406 PSNVLQPLHIERCFGVLVAPGKLVVQKDMHLIDMHSMGYIQPGGTGVATESDSNAQ----QSSSW 466
            .|::.:.||.:                  ..|...|......|...:..:|||::.    :|...
Mouse   690 DSHLHRMLHRD------------------STISNESSQSCSSGRQNLRLQSDSSSSTQVFESVDE 736

  Fly   467 PYTIRAEWKAQEKAFEQLNLESSKTNLTVAVDIVMRRIQEPVRFVIETPVTIQSASEMRIMDHFM 531
            .....||.:::||..:..|  .:..|.|.:.|     ...|......:.::..|...:...|..:
Mouse   737 VEQTEAEGRSEEKHPKIPN--GNPANGTCSPD-----SGHPSSHNFSSGLSEHSEPSLSTEDSVL 794

  Fly   532 -SKRPMTLRFYLHLKRTE--ESNWKVNSID--PSEEITEQPGHQQSSSLLKMGMNNLSRIVRSSS 591
             ::|.:...|.......|  :|:....|.|  |.||:..|.. .:|..|....:.....|..|..
Mouse   795 DAQRSLPAVFRPGDSSVEDGQSSEATTSRDEAPREELAVQDS-LESDLLANESLEEFMSIPGSLD 858

  Fly   592 IASIEDD--CPSDYSSDGDEPLLSGTGEVSKDCSQDTLDEWDPILREWDSEKRPKNLAP-LVRLG 653
            :|..|.|  ....:..:.|:|        |:..|:|.|.|          |...::|.| |..|.
Mouse   859 VALPEKDGAVMDGWPGEADKP--------SRADSEDNLSE----------EPEMESLFPALASLA 905

  Fly   654 V-PEALREKIWQKLANVEGRMEMNDKYKILITKETKCETVIQRDIHRTFPAHKCFKEIGGSGQDA 717
            | ..|..|......:.|....|:.|.|.:.:.:       |::|:.|...::..|.   .:..:.
Mouse   906 VTSSANNEASPVSSSGVTYSPELLDLYTVNLHR-------IEKDVQRCDRSYWYFT---AANLEK 960

  Fly   718 LFKVSKAYAVHDSEVGYCQGLSFIAASLLLHMPEED-AFCVLVALMYDYGLRDLYKAGFEVLYLR 781
            |..:..:|.....|:||.||:..:.|.||:.:.:|. ||.....||........:....:..:..
Mouse   961 LRNIMCSYIWQHIEIGYVQGMCDLLAPLLVILDDEALAFSCFTELMKRMNQNFPHGGAMDTHFAN 1025

  Fly   782 LYQLERLIKDQLPKL-HEHFTACGIETHMY-ASQWFLTLYTARFPLCFVFHVLDVF-----LLDG 839
            :..|.:::..:|.:| |::    |..||.| ..:|||..:........||.|.:..     :...
Mouse  1026 MRSLIQILDSELFELMHQN----GDYTHFYFCYRWFLLDFKRELVYDDVFSVWETIWAAKHVSSA 1086

  Fly   840 LPVLFQVAVTLLSICESDL--RQLDFEGILKYF 870
            ..||| :|:.|:.:....:  ..:||..|:|:|
Mouse  1087 HYVLF-IALALVEVYRDIILENNMDFTDIIKFF 1118

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GAPcenA	NP_001097549.1	PTB_Rab6GAP	204..332	CDD:269922	12/55 (22%)
		DUF3694	429..523	CDD:289256	17/97 (18%)
		TBC	650..858	CDD:214540	46/216 (21%)
		Phage_Gp23	<914..991	CDD:287621
Sgsm1	XP_006535185.1	RUN	44..186	CDD:367169
		PH_RUTBC	254..425	CDD:275431
		TBC	<936..1105	CDD:214540	38/183 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900