Protein Alignment GAPcenA and Tbc1d5

DIOPT Version :9

• Sequence 1: NP_001097549.1
• Gene: GAPcenA / 38945
• FlyBaseID: FBgn0035879
• Length: 1194
• Species: Drosophila melanogaster
• Sequence 2: XP_008764990.1
• Gene: Tbc1d5 / 501088
• RGDID: 1561626
• Length: 827
• Species: Rattus norvegicus
• Alignment Length: 860
• Identity: 166/860 - (19%)
• Similarity: 271/860 - (31%)
• Gaps: 308/860 - (35%)

  Fly   591 SIASIEDDCPSDYSSDGDEPLLSGTGEVSKDCSQD------TLD---EWDPILREWDSEKRPKN- 645
            |::.......|:....|.:||.|.:.:...|..|:      .||   .:...:||||......|
  Rat     4 SVSETRHPLQSEEQEVGIDPLFSYSNKPRGDSCQNGRGANSNLDCDGTFSSYMREWDDLFVNNNY 68

  Fly   646 LAPLVRLGVPEALREK-----IW------------QKLANVEGRMEMNDKY----KILIT----- 684
            ||.:.:.|:...||..     .|            |.::.::   |:...|    :|.||
  Rat    69 LAAVRQKGINGQLRSSRFRSICWKLFLCVLPQDKSQWISRIK---ELRSWYSNIKEIHITNPRKV 130

  Fly   685 ------------------------KETKCETVIQRDIHRTFPAHKCFKE--IGGSGQDALFKVSK 723
                                    ::.:..::|::|:.||||..:.|::  :.....|.||
  Rat   131 VGQQDLMINNPLSQDEGSLWNKFFQDKELRSMIEQDVRRTFPEMQFFQQENVRKILTDVLF---- 191

  Fly   724 AYAVHDSEVGYCQGLSFIAASLL----------LHMP------------------EEDAFCVLVA 760
            .||..:.::.|.||:..:.|.::          ||..                  |.||:.:...
  Rat   192 CYARENEQLLYKQGMHELLAPIIFTLHCDHQAFLHASESAQPSEEMKTLLNPEYLEHDAYAMFSQ 256

  Fly   761 LM------YDYGLRDLYKAGFEVL-----YLRLYQL--------------ERLIKDQLPKLHEHF 800
            ||      :.....|..| |.|.|     :.|...|              :.|:|....:|:.|.
  Rat   257 LMETAEPWFSTFEHDGQK-GKETLMPPIPFARPQDLGPTVAIVTKVNQIQDHLLKKHDTELYMHL 320

  Fly   801 TACGIETHMYASQWFLTLYTARFPLCFVFHVLDVFLLDGL----------PVLFQVAVTLLS--- 852
            ....|...:|..:|...|:...|||..:..|.|....|||          .:|..:...|:|
  Rat   321 NRLEIPPQIYGLRWVRLLFGREFPLQDLLVVWDALFADGLHLSLVDYVFTAMLLYIRDALISSNY 385

  Fly   853 -ICESDLRQLDFEG-----ILKYFRVTLPKKCRSSSQARKVMKQACERKIKKLKQYEEEFLLKKQ 911
             .|...|......|     |||...:..||:     ..|.|..| ....:...|....:.:.|.:
  Rat   386 QTCLGLLMHYPLIGDIHSLILKALFLRDPKR-----NPRPVTYQ-FHPNLDYYKARGADLMNKSR 444

  Fly   912 HKER-----LEKEAQIYENRFGEERRKMQAEIDALNKQ-------------------LTSAKERA 952
            ...|     :.|.:....| ||   ||:.|...|....                   .|||:...
  Rat   445 TNARGAPLNIHKVSNSLIN-FG---RKLIAPASAPGSMGGPVPGSNSSSSFSAAVPFRTSAEAPR 505

  Fly   953 VEKEKKHTGIIQEYKQIIQRQEQDMNTL--SETL--------------GKVMHMVSNCQDCQQQ- 1000
            ...:::.....|:.:|..|:|:|....|  ||::              .:|...|....|.|.|
  Rat   506 HHSQQQRQQQQQQQQQQQQQQQQQQQRLMKSESMPVQLNKGDVVTGSDAQVSVPVQALTDLQGQS 570

  Fly  1001 ------------IDAG-------------NDNAKSDDGKNRGQTDAM-RNANEHPLGPLDPLNAA 1039
                        :..|             .|:..|...::|..:.|| |..:|..|
  Rat   571 PKTISSSPSMESLPGGREPPGSPPSSATKRDSFFSHIARSRSHSKAMGRKESEEEL--------- 626

  Fly  1040 SQRIRELELELAQAKLAQVEAECK--------------------NQDLNHQLSNTLSELQTNRNS 1084
                 |.::...|.:|..::|.||                    |.:...|:..:|:.|:..::.
  Rat   627 -----EAQISFLQGQLNDLDAMCKYCAKVMDMHLVNIQDVVLQENLEKEDQILVSLAGLKQIKDI 686

  Fly  1085 WQPWLSKTFNSLQ------EKVTTRGGH-----RDNGSGGP---------MP------------- 1116
            .:.  |..||..|      |::|....|     :|.|:.||         ||
  Rat   687 LKG--SLRFNQSQLEAEENEQITIADDHYCSSGQDQGTQGPRAAKQASSEMPGCTGGATSDDFIL 749

  Fly  1117 ---------SFQSYMGQAPTTLSEASSPSGNQEYKT-----FAFASVG---GSPKLPSKFQATKL 1164
                     :.:::.|||...|: ..:.||.....|     |:...:|   .|...||  .:...
  Rat   750 VSKEDEGRRAKEAFSGQAQPLLT-LRNTSGKSRVPTCSPLVFSDPLMGPASASSSNPS--SSPDD 811

  Fly  1165 RNSIDSLRNIVVPLD 1179
            .:|.||...||.|||
  Rat   812 DSSKDSGFTIVSPLD 826

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GAPcenA	NP_001097549.1	PTB_Rab6GAP	204..332	CDD:269922
		DUF3694	429..523	CDD:289256
		TBC	650..858	CDD:214540	60/326 (18%)
		Phage_Gp23	<914..991	CDD:287621	21/116 (18%)
Tbc1d5	XP_008764990.1	TBC	79..381	CDD:214540	56/309 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900