DRSC/TRiP Functional Genomics Resources

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Protein Alignment GAPcenA and tbc1d16

DIOPT Version :9

Sequence 1:NP_001097549.1 Gene:GAPcenA / 38945 FlyBaseID:FBgn0035879 Length:1194 Species:Drosophila melanogaster
Sequence 2:NP_001006076.2 Gene:tbc1d16 / 450056 ZFINID:ZDB-GENE-041010-179 Length:717 Species:Danio rerio


Alignment Length:596 Identity:119/596 - (19%)
Similarity:198/596 - (33%) Gaps:205/596 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly   438 DMHSMGYIQPGGTGVATESDSNAQQSSSWPYTIRAEWKA-----QEKAFEQLNLESSKTNLTVAV 497
            |..::.||.|..:.|.......|.:|.|.|.....|.:|     ||...:.|..|..:.:..::.
Zfish    89 DEEALRYITPESSPVRRNPRRRAHRSHSRPPAAPEEEEAADEEGQEPQNQALLEEGDEGSCELSA 153

  Fly   498 DIVMRRIQEPVRFVIETPVTIQSASEMRIMDHFMSKRPMTLRFYLHLKRTEESNWKVNSIDPSEE 562
            |.|.|            ..||.|.|     |.|.|  |..|                      ..
Zfish   154 DEVSR------------DSTIGSDS-----DTFSS--PFCL----------------------SP 177

  Fly   563 ITEQPGHQQSSSLLKMGMNNLSR------IVRSSSIASIEDDCPSDYS-SDG------------- 607
            ::|..|...||..|    :|.||      ...:||.:|::...||:.| |.|             
Zfish   178 VSEALGESSSSVFL----DNESRECDEPMAHSASSASSLDSHAPSESSHSQGVRWEEQQNVMALE 238

  Fly   608 ---------------------DEPLLSGTGEVSKDCSQ--------DTLDEWDPILREWD----- 638
                                 ||....|...::...||        ..||:...:.::|.     
Zfish   239 HLCGVFRVDLGHMRSLRLFFSDEACTCGQLVIASRESQYKILHFHHAGLDKLAEVFQQWKCCRET 303

  Fly   639 ---------------SEKRP----KNLAPLVRL-------------------------------- 652
                           |.:||    ..:.|..||                                
Zfish   304 QLKDQVSDEKSCMQFSIRRPTLPSAEMHPEERLYRRLDVSSWLRHLNNSGQVLEEYKLRKAIFFG 368

  Fly   653 GVPEALREKIWQKLAN---------------VEGRMEMND--KYKILITKE------TKCETVIQ 694
            |:..::|.::|..|.:               ::.|.|..|  :.::.::.|      .|.:..:.
Zfish   369 GIDPSIRGEVWPFLLHYYSYDSTSEEREAWRLQKRGEYQDIQQRRLSMSPEEHSEFWRKVQFTVD 433

  Fly   695 RDIHRTFPAHKCFKEIGGSGQDALFKVSKAYAVHDSEVGYCQGLSFIAASLLLHMPEE-DAFCVL 758
            :|:.||..::..|:.......:.:.::...|||.:.::|||||:|.:.|.||..:.:| |.|...
Zfish   434 KDVVRTDRSNMFFRGENNPNVEIMRRILLNYAVFNPDMGYCQGMSDLVAPLLTEIQDESDTFWCF 498

  Fly   759 VALM----YDYGLRDLYKAGFEVLYLRLYQLERLIKDQLPKLHEHFTACGIE--THMYASQWFLT 817
            |.||    :....||      |.:..:|..|..|::..||:.|:|.|..|.:  ..::..:|.|.
Zfish   499 VGLMENTIFISSPRD------EDMERQLMYLRELLRLMLPRFHQHLTRLGEDGLQLLFCHRWVLL 557

  Fly   818 LYTARFP---------LCFVFHVLD---VFLLDGLPVLFQVAVTLLSICESDLRQLDFEGILKYF 870
            .:...||         .|:..:..|   :||...:.||:...||...:. :|...|.|..:..:.
Zfish   558 CFKREFPDAEALRMWEACWAHYQTDYFHLFLCVAIIVLYGDDVTEQQLA-TDQMLLHFSNLSMHM 621

  Fly   871 RVTLP-KKCRS 880
            ...|. :|.||
Zfish   622 NGELVLRKARS 632

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GAPcenANP_001097549.1 PTB_Rab6GAP 204..332 CDD:269922
DUF3694 429..523 CDD:289256 21/89 (24%)
TBC 650..858 CDD:214540 57/281 (20%)
Phage_Gp23 <914..991 CDD:287621
tbc1d16NP_001006076.2 TBC 368..596 CDD:214540 52/233 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5210
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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