DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GAPcenA and CG5916

DIOPT Version :9

Sequence 1:	NP_001097549.1	Gene:	GAPcenA / 38945	FlyBaseID:	FBgn0035879	Length:	1194	Species:	Drosophila melanogaster
Sequence 2:	NP_001287357.1	Gene:	CG5916 / 41960	FlyBaseID:	FBgn0038401	Length:	330	Species:	Drosophila melanogaster

Alignment Length:	268	Identity:	70/268 - (26%)
Similarity:	121/268 - (45%)	Gaps:	42/268 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   629 EWDPILRE-WDSEKRPKNLAPLVRLGVPEALREKIWQKLANVEGRMEMN-DKYKILITKE---TK 688
            :|:.||:: .|..:....|...:|.|:|...|..:|.|::........: |.::.|:..|   .:
  Fly    45 KWEAILQQNTDLTQVDAKLKRYIRKGIPGPYRPDVWMKISGAAAAQRRSPDLFRNLLRTEPFDKE 109

  Fly   689 CETVIQRDIHRTFPAHKCFKEIGGSGQDALFKVSKAYAVHDSEVGYCQGLSFIAASLLLHM-PEE 752
            ....|..|:.||||.:..|    ...:..|:.:..|||.|:.:|||||||::||..||:.. .||
  Fly   110 ISDSISIDLPRTFPDNIHF----DMKKQRLYNILIAYAHHNRDVGYCQGLNYIAGLLLIVTDDEE 170

  Fly   753 DAFCVL-------VALMYDYG----LRDLYKAGFEVLYLRLYQLERLIKDQLPKLHEHFTACGIE 806
            .:|.:|       |...:.:.    ||||  |.|..|.:|          ::|.::.|....|:.
  Fly   171 KSFWLLKHIVENIVPQYHSHNMANLLRDL--AVFRELVIR----------RIPAVNRHVDNLGLP 223

  Fly   807 THMYASQWFLTLYTARFPLCFVFHVLDVFLLDGLPVLFQVAVTLL-----SICESDLRQLDFEGI 866
            ..:.||:||:.::....|:..|..:.|....:|..::|:.|:|:.     :|...|    |...:
  Fly   224 YPVIASKWFICIFAEVLPVETVLRIWDCVFAEGYKIVFRAALTMFVTHKNAILGCD----DIAAL 284

  Fly   867 LKYFRVTL 874
            ...||.|:
  Fly   285 ANLFRDTM 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GAPcenA	NP_001097549.1	PTB_Rab6GAP	204..332	CDD:269922
		DUF3694	429..523	CDD:289256
		TBC	650..858	CDD:214540	60/228 (26%)
		Phage_Gp23	<914..991	CDD:287621
CG5916	NP_001287357.1	TBC	67..276	CDD:214540	59/224 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456588
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22957
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840