Protein Alignment GAPcenA and CG12241

DIOPT Version :10

• Sequence 1: NP_001097549.1
• Gene: GAPcenA / 38945
• FlyBaseID: FBgn0035879
• Length: 1194
• Species: Drosophila melanogaster
• Sequence 2: NP_650432.1
• Gene: CG12241 / 41834
• FlyBaseID: FBgn0038304
• Length: 804
• Species: Drosophila melanogaster
• Alignment Length: 622
• Identity: 130/622 - (20%)
• Similarity: 232/622 - (37%)
• Gaps: 160/622 - (25%)

  Fly   563 ITEQPGHQQSSSLLKMGMNNLSRIVRSSSIASIEDDCPSDYSSDGDEPLLSGTGEV----SKDCS 623
            :.|:.|.:|||:.|             .||..:||          .:..|.....:    :|:.:
  Fly    99 VEEEDGPEQSSNKL-------------LSIPFVED----------AQQRLQWIAHLEFSHNKEAA 140

  Fly   624 QDTLDEWDPILREWDSEKRPKNLAPLVRLGVPEALREKIWQKLANVEGRMEMND-KYKILITKET 687
            :.:.:..|.:|      .|.:.|..:||.|:|..||.::|.:|:....:.:.:: .|..::...:
  Fly   141 ELSWEHVDVML------PRTEKLRNMVRQGIPHTLRAQMWMRLSGALAKKQKSETSYHDIVKASS 199

  Fly   688 KCETV----IQRDIHRTFPAHKCFKEIGGSGQDALFKVSKAYAVHDSEVGYCQGLSFIAASLLLH 748
            ..:.:    |::|:.|..|.:.||....|:|...|.::.:..|....::|||||...|.|.|||.
  Fly   200 NDQLMTSKQIEKDLLRILPTNACFSNPNGTGIPRLRRILRGIAWLFPDIGYCQGTGVIVACLLLF 264

  Fly   749 MPEEDAFCVLVALMYDYGLRDLYKAGF---EVLYLRLYQ--LERLIKDQLPKLHEHFTACGIETH 808
            |.||:||.::..:     :.||..|.:   .:|.::..|  :..||.:.|..:.|......||..
  Fly   265 MEEENAFWMMATI-----VEDLLPASYYSSTLLGIQADQRVMHTLIANYLSSVDESLRKHDIELS 324

  Fly   809 MYASQWFLTLYTARFPLCFVFHVLDVFLLDGLPVLFQVAVTLLSICESDLRQLD-----FEGI-- 866
            :....|||||:.....:..:..:.|.|..:|..||||:.:.:|.:.|.||:.|:     |..:
  Fly   325 LITLHWFLTLFANVVHMKILVRIWDWFFYEGSIVLFQLTLGMLKVKEQDLKHLENSAQIFNSLSD 389

  Fly   867 ----------------------------------LKYFRVTLPKKCRSSSQARKVMK-QACERKI 896
                                              |.|.......:..:...|..:.| |...|::
  Fly   390 IPGEVTDVEVLFRQALEVGGSLSQTVIDTHRRRHLAYLMADQGHQIGNPEAAPNLPKQQLARRQV 454

  Fly   897 KKLKQYEEEFL----------LKKQHKERLE-----KEAQIYENR-FGEERRKMQAEIDALNKQL 945
            :|.|...|.||          ||.::..:.|     :||.:...| |.....|:...|     ||
  Fly   455 RKSKSILEAFLFRGDGNEGDQLKNKNIRQTEILVDLREAILKVGRHFITIEPKLAGHI-----QL 514

  Fly   946 TSAKERAVEKEKKHTGII-------QEYKQIIQRQEQDMNTLSETLGKVMHMVSNCQD-C----- 997
            | |........|.|...|       :..|.:...:..|.:.|......::.::|...: |
  Fly   515 T-ANYSTESHAKDHENFINVARTRKRRAKALHDFERHDDDELGFRRNDIITIISQKDEHCWVGEL 578

  Fly   998 --------QQQIDAGNDNAK-----SDDGKNRGQTDAMRNA--------NEHPL-------GPLD 1034
                    .:.::..::.:|     .||..:...||.:|..        .||.:       ||:.
  Fly   579 NGLRGWFPAKFVELLDERSKLYTSAGDDAISETVTDLVRGTLAPAIKAFLEHGMKRPTFLGGPIH 643

  Fly  1035 P---LNAASQRIRELELELAQAKLAQVEAECKNQDLN 1068
            |   :..|:.|..|.:.|...::|..    ||...|:
  Fly   644 PWLYIEEAATREVEKDFESVYSRLVL----CKTYRLD 676

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GAPcenA	NP_001097549.1	PTB_Rab6GAP	204..332	CDD:269922
		DUF3694	377..523	CDD:463599
		TBC	650..858	CDD:214540	59/217 (27%)
		SMC_prok_B	<876..>1087	CDD:274008	49/254 (19%)
		TPH	<883..>977	CDD:464007	26/117 (22%)
CG12241	NP_650432.1	TBC	161..375	CDD:214540	60/218 (28%)
		SH3_SGSM3	540..592	CDD:212747	5/51 (10%)
		RUN_SGSM3	570..783	CDD:439050	20/111 (18%)