Protein Alignment GAPcenA and CG42795

DIOPT Version :10

• Sequence 1: NP_001097549.1
• Gene: GAPcenA / 38945
• FlyBaseID: FBgn0035879
• Length: 1194
• Species: Drosophila melanogaster
• Sequence 2: NP_001287272.1
• Gene: CG42795 / 41252
• FlyBaseID: FBgn0261928
• Length: 3213
• Species: Drosophila melanogaster
• Alignment Length: 786
• Identity: 175/786 - (22%)
• Similarity: 287/786 - (36%)
• Gaps: 199/786 - (25%)

  Fly   495 VAVDIVMRRIQEPVRFVIETPVTIQSASEMRIMDHFMSKRPMTLRFYLHLKRTEESNWKVNSIDP 559
            ||.|.:.|..:....||  |.|.|..:.:.:....| |..|...:.....:.|..:.   ||:..
  Fly    91 VARDRLQRHQEVLCEFV--TAVLIVESDDAQPKMRF-SLSPPPQKAITSARLTSPTK---NSLSS 149

  Fly   560 SEEITEQPGHQQSSSLLKMGMNNLSRIVRSSSIASIEDDCPSDYSSDGDEPLLSGTGEV-SKDCS 623
            :..||....:.:|.|..|..|  |:|                :....|..|..||:|.. |...:
  Fly   150 NNTITTPGSNNRSPSSTKTTM--LTR----------------NGGGHGTSPTASGSGHAPSATAA 196

  Fly   624 QDTLDEWDPILREWDSEKRPKNLAPLVRLGVPEALREKIWQKLANVEGRMEMNDKYKILITKET- 687
            .|  ||......:|   .....|...:..|.|...|.|:|..||         |||  |.:|..
  Fly   197 AD--DEATSDYNQW---LHAMKLVARLPGGTPPEFRRKLWLSLA---------DKY--LKSKNVD 245

  Fly   688 ------KC----------ETVIQ--RDIHRTFPAHKCFKEIGGSGQDALFKVSKAYAVHDSEVGY 734
                  ||          |..||  :|:||| .::.|....|...|..|.::...||.::.||||
  Fly   246 WAQQREKCFCEEWREDDEELGIQIVKDLHRT-GSNLCTGPAGSINQAKLKRILLGYARYNPEVGY 309

  Fly   735 CQGLSFIAASLL--LHMPEEDAFCVLVALM-------YDYGLRDLYKAGFEVLYLRLYQLERLIK 790
            |||.:.:.|.:|  :...||::..|::.|:       |.||.....:|...|       ...|::
  Fly   310 CQGFNMLGALILQVMDKEEEESMKVMIYLVEGVLPTGYFYGSMGGLQADMGV-------FRELMQ 367

  Fly   791 DQLPKLHEHFTAC--GIE-------THMYASQWFLTLYTARFPLCFVFHVLDVFLLDGLPVLFQV 846
            .:||:|.:|....  .:|       |:::..|||||::....|:..|..|.|:.|::|..||.:.
  Fly   368 TRLPRLAKHLQRLQGPVENAFEPPLTNVFTMQWFLTMFCTCLPMSCVLRVWDLVLIEGSDVLLRT 432

  Fly   847 AVTLLSICES---DLRQLD-FEGILKYFRVTL--PKKCRSSSQARKVMKQACERKIKKLKQYEEE 905
            |:.|.|:.|.   .:|..| |.|.:..:...|  .....|:....:|:|..   .|:.|:|..::
  Fly   433 ALVLWSLLEERVISVRSADEFYGKMGSYSSELLNGHLVDSNGLIERVVKLG---PIEDLRQLRDK 494

  Fly   906 FLLK---KQHKERLEKEAQIY---ENRFGEERRKMQAEIDALN-------KQLTSAKERAVEKEK 957
            .|..   .:||:.|    |:|   |:...:|.|...|.:..||       ....:.|::..:|::
  Fly   495 HLYNIAPLRHKQGL----QLYYDEEDTHSDEERLAVATVFGLNWGRRGSVGPAAAGKQQVEQKDR 555

  Fly   958 KHTGII---QEYKQIIQRQEQDMNTLSETLGKVMHMVSNCQDCQQ------QIDAGNDNAKSDDG 1013
            ....|.   ::|.::.:||:|....|:..........|......|      |:..|.....::.|
  Fly   556 LALDISLLKKQYDRLRERQKQAHVILTTACSTAARQGSGPASSSQPAVPVNQLLLGRPAIVTNKG 620

  Fly  1014 KNRGQTDAMRNANEHPLGPLDPLNAAS-------QRIRELELELAQAKL-AQVEAECKNQDLNHQ 1070
            |..|.          |||.:.|....|       :...|.:|...:..| ...:...:.:|
  Fly   621 KRVGA----------PLGAIPPARKPSLPAVLHTKPTSEKQLRRGETLLWRDTDPSRRRRD---- 671

  Fly  1071 LSNTLSELQTNRNSWQPWLSKTFNSLQEKVTTR-------------GGHRDNGSGGPMPSFQSYM 1122
             |.|..|::.:|.:.........:...:|:.||             .|.:::|:||...|
  Fly   672 -SLTWKEIKADRAAMIREGVDVSSVRTQKLRTRFGKSDSSSYSEDSDGEQESGTGGGGGS----- 730

  Fly  1123 GQAPTTLSEASSPSGNQEYKTFAFASVGGSPKLPSKFQATKLRNSIDSLRNIVVPLDTGKTLAEN 1187
             ...|:|.:...|...::           |||..:|                         ||..
  Fly   731 -STDTSLCDDDDPKSTEK-----------SPKQKAK-------------------------LARK 758

  Fly  1188 LKQQLQ 1193
            ||:|.|
  Fly   759 LKEQKQ 764

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GAPcenA	NP_001097549.1	PTB_Rab6GAP	204..332	CDD:269922
		DUF3694	377..523	CDD:463599	9/27 (33%)
		TBC	650..858	CDD:214540	69/247 (28%)
		SMC_prok_B	<876..>1087	CDD:274008	46/240 (19%)
		TPH	<883..>977	CDD:464007	24/109 (22%)
CG42795	NP_001287272.1	RabGAP-TBC	268..443	CDD:459855	53/182 (29%)
		DUF4682	560..689	CDD:464830	26/143 (18%)
		PTZ00121	<1112..2009	CDD:173412
		PTZ00121	<1740..2340	CDD:173412
		PTZ00449	<2270..2610	CDD:185628