DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment GAPcenA and grtp1a

DIOPT Version :9

Sequence 1:	NP_001097549.1	Gene:	GAPcenA / 38945	FlyBaseID:	FBgn0035879	Length:	1194	Species:	Drosophila melanogaster
Sequence 2:	NP_998567.1	Gene:	grtp1a / 406711	ZFINID:	ZDB-GENE-040426-2733	Length:	356	Species:	Danio rerio

Alignment Length:	363	Identity:	95/363 - (26%)
Similarity:	158/363 - (43%)	Gaps:	67/363 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   564 TEQPGHQ--QSSSLLKMGMNNLSRIVRSSSIASIEDDCPSDYSSDGDEPLLSGTGEVSKDCSQDT 626
            |.||.|:  |.|:..:          |::|:.:.......|:..:..|.|:|   |.....::.:
Zfish    10 TGQPQHRINQPSTARE----------RANSVDAYGFQRSDDFDYETHEQLMS---EYLAVLTRRS 61

  Fly   627 LDEWDPILREWDSEKRPKNLAPLVRLGVPEALREKIWQKLANVEGRMEMNDKY--KILIT-KETK 688
            : .|..:|:......|...:...||.|||...|..:|...:..:.:|:.|..|  .:|.| .|.|
Zfish    62 I-RWAKLLQGRRRVDRNLKVKRYVRKGVPNEHRPLVWMVCSGAQEQMDRNPGYYQSLLDTHHEPK 125

  Fly   689 CETVIQRDIHRTFP--------AHKCFKEIGGSGQDALFKVSKAYAVHDSEVGYCQGLSFIAASL 745
            .|..|:.|:|||||        |..|.       |.||:.|..||..|:..||||||::|||..|
Zfish   126 LEESIRTDLHRTFPDNIYFRKSAEPCL-------QQALYNVLVAYGHHNKAVGYCQGMNFIAGYL 183

  Fly   746 LL-HMPEEDAFCVLVALMY----DY------GLRDLYKAGFEVLYLRLYQLERLIKDQLPKLHEH 799
            :| ...||.:|.::.||:.    ||      ||:...:...|::.|:...:.:|::||
Zfish   184 ILVSKDEETSFWLMEALLSRILPDYYTPAMLGLKTDQEVLGELVRLKAPAVWKLMQDQ------- 241

  Fly   800 FTACGIETHMYASQWFLTLYTARFPLCFVFHVLDVFLLDGLPVLFQVAVTLLSICESDLRQLDFE 864
                |:...:..|:||:.|:....|:..|..:.|....:|..:||:||:||:...:.::.:..
Zfish   242 ----GVMWTLVVSRWFICLFIDVLPVETVLRIWDCLFYEGSKILFRVALTLIRHHQQEIAEAQ-- 300

  Fly   865 GILKYFRVTLPKKC-RSSSQARKVMKQACERKIKKLKQ 901
                    .||..| |.....|....:.|...::|:.|
Zfish   301 --------NLPDVCERFKRITRGAFVEDCHTFMQKIFQ 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GAPcenA	NP_001097549.1	PTB_Rab6GAP	204..332	CDD:269922
		DUF3694	429..523	CDD:289256
		TBC	650..858	CDD:214540	71/229 (31%)
		Phage_Gp23	<914..991	CDD:287621
grtp1a	NP_998567.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..29		7/28 (25%)
grtp1a	NP_998567.1	TBC	84..296	CDD:214540	71/229 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910