DRSC/TRiP Functional Genomics Resources

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Protein Alignment GAPcenA and Tbc1d10c

DIOPT Version :9

Sequence 1:NP_001097549.1 Gene:GAPcenA / 38945 FlyBaseID:FBgn0035879 Length:1194 Species:Drosophila melanogaster
Sequence 2:NP_001075449.1 Gene:Tbc1d10c / 361697 RGDID:1311490 Length:446 Species:Rattus norvegicus


Alignment Length:448 Identity:110/448 - (24%)
Similarity:185/448 - (41%) Gaps:94/448 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   593 ASIEDDCP---SDYSSDGDEPLLS--------------GTGEVSKDCSQDTLDEWDPILREWDS- 639
            :.::||..   ||....|..|...              |.|:...|..:....:|..:...|:. 
  Rat    13 SELQDDSSSLGSDSEISGSSPYRQADRYGFIGGNSAELGLGQPPADLIRQREMKWVEMTLHWEKT 77

  Fly   640 -EKRPKNLAPLVRLGVPEALREKIWQKLANVEGRMEMN-DKYKILITK--ETKCETVIQRDIHRT 700
             .:|.|.:....|.|:|.|||.:.|..|.......:.| ..|:.|...  :.:....|.||:||.
  Rat    78 MSRRYKKVKIQCRKGIPSALRARCWPLLCGAHMCQKNNPGTYQELAVAPGDPQWMETIGRDLHRQ 142

  Fly   701 FPAHKCFKEIGGSGQDALFKVSKAYAVHDSEVGYCQGLSFIAASLLLHMPEEDAFCVLVALMYDY 765
            ||.|:.|....|.||..|.:|.|||.::..|.||||....:||.||:|:|.|:||..||.:.   
  Rat   143 FPLHEMFVSPQGHGQQGLLQVLKAYTLYRPEQGYCQAQGPVAAVLLMHLPPEEAFWCLVQIC--- 204

  Fly   766 GLRDLYKAGFEVLYLRLYQLE-----RLIKDQLPKLHEHFTACGIETHMYASQWFLTLYTARFPL 825
               ::|..|:...::...||:     .|::..||::::|....|:...:|..:|||.|:|...|.
  Rat   205 ---EVYLPGYYGPHMEAVQLDAEVFMALLRRLLPRVYKHLQQVGVGPLLYLPEWFLCLFTRSLPF 266

  Fly   826 CFVFHVLDVFLLDGLPVLFQVAVTLLSICESDLRQ-------LDFEGILKYFRVTLPKKCRSSSQ 883
            ..|..:.|.||.:|..|||:..:||:.:....:.|       |:..|.|:    |:|.       
  Rat   267 PIVLRIWDAFLSEGAKVLFRAGLTLMRLALGTVEQRTACPGLLETLGALR----TIPP------- 320

  Fly   884 ARKVMKQACERKIKKLKQYEEEFLLKKQHKERL-EKEAQIYENRFGEERRKMQAEIDALNKQ--- 944
                            .|.:||..:.:.|...| |::.|          |:::.::..|.|.   
  Rat   321 ----------------TQLQEEVFMSQVHNVALSERDLQ----------REIRIQLAQLPKSSPG 359

  Fly   945 ---LTSAK---ERAVEKEKKHTGI----IQEYKQIIQRQEQDMN---TLSETLGKVMH 989
               |..|:   .:|:.:.::..|:    ..|..:|:.:..::.|   ...:|.||..|
  Rat   360 PVPLPQARLPGAQAIFESQQLAGMRGGAKPEIPRIVVQPPEEPNPPRRKPQTRGKTFH 417

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GAPcenANP_001097549.1 PTB_Rab6GAP 204..332 CDD:269922
DUF3694 429..523 CDD:289256
TBC 650..858 CDD:214540 70/215 (33%)
Phage_Gp23 <914..991 CDD:287621 17/93 (18%)
Tbc1d10cNP_001075449.1 TBC 89..294 CDD:214540 70/210 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5210
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

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