DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GAPcenA and GstT3

DIOPT Version :9

Sequence 1:	NP_001097549.1	Gene:	GAPcenA / 38945	FlyBaseID:	FBgn0035879	Length:	1194	Species:	Drosophila melanogaster
Sequence 2:	NP_001162808.1	Gene:	GstT3 / 33047	FlyBaseID:	FBgn0031117	Length:	268	Species:	Drosophila melanogaster

Alignment Length:	300	Identity:	55/300 - (18%)
Similarity:	98/300 - (32%)	Gaps:	109/300 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   484 LNLESSKTNLTVAVDIVMRRIQEPVRFVIETPVTIQSASEMRIMDHFMSK--RPMTLRFYLHLKR 546
            |.|.:.:..|.||.|.|::|     |.....|..::.::.:|.....||:  |.:.:.|.|....
  Fly    10 LGLSNDEDQLQVAFDEVLKR-----RVPSRQPTNLRMSAPIRYYYDLMSQPSRALFIIFRLSNMP 69

  Fly   547 TEESNWKVNSIDPSEEITEQPGHQQSSSLLKMGMNNLSRI--------VRSSSIASIEDDCPSDY 603
            .|:.   |.::...|.:||.         .|..:|...|:        ..:.|:|.:.
  Fly    70 FEDC---VVALRNGEHLTED---------FKKEINRFQRVPCIHDNGYKLAESVAILR------- 115

  Fly   604 SSDGDEPLLSGTGEVSKD------CSQDTLDEWDPILREWDSEK---------RPKNLAPLVRLG 653
                   .||..|::.:.      ..|..:||:    .||....         |...|.||:...
  Fly   116 -------YLSAKGKIPEHLYPKYFVDQSRVDEF----LEWQHMSLRLTCAMYFRTVWLEPLLTGR 169

  Fly   654 VP-----EALR----------EKIWQKLANVEGR-------MEMNDKYKILITKETKCETVIQRD 696
            .|     |..|          |::|     :||:       :.:.|.:.....::|:   :...|
  Fly   170 TPSEAKIETFRMQMERNLDVVEEVW-----LEGKDFLTGSSLTVADIFAACEIEQTR---MADYD 226

  Fly   697 IHRTFP-------------------AHKCFKEIGGSGQDA 717
            :...:|                   ||:...:|.|:|..|
  Fly   227 VRIKYPKIRAWLKRVRQSCNPYYDVAHEFVYKISGTGPQA 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GAPcenA	NP_001097549.1	PTB_Rab6GAP	204..332	CDD:269922
		DUF3694	429..523	CDD:289256	10/38 (26%)
		TBC	650..858	CDD:214540	16/108 (15%)
		Phage_Gp23	<914..991	CDD:287621
GstT3	NP_001162808.1	GST_N_Theta	45..121	CDD:239348	18/101 (18%)
		GstA	47..243	CDD:223698	38/233 (16%)
		GST_C_Theta	135..259	CDD:198292	22/135 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900