Protein Alignment GAPcenA and Evi5l

DIOPT Version :10

• Sequence 1: NP_001097549.1
• Gene: GAPcenA / 38945
• FlyBaseID: FBgn0035879
• Length: 1194
• Species: Drosophila melanogaster
• Sequence 2: NP_001418968.1
• Gene: Evi5l / 304201
• RGDID: 1561962
• Length: 815
• Species: Rattus norvegicus
• Alignment Length: 587
• Identity: 174/587 - (29%)
• Similarity: 291/587 - (49%)
• Gaps: 67/587 - (11%)

  Fly   547 TEESNWKVNSIDPSEEITEQPGHQQSSSLLKMGMNNLSRIVRSSSIASIEDDCPSDYSSDGDEPL 611
            ::..|...:.::...::.||....::.|.....||...|...||.::|      |..||:
  Rat    30 SDSENLSPDELELLAKLEEQNRLLEADSKSMRSMNGSRRNSGSSLVSS------SSASSN----- 83

  Fly   612 LSGTGEVSKDCSQDTLDEWDPILREWDSEKRPKN--LAPLVRLGVPEALREKIWQKLANVEGRME 674
            ||       ...:||...|..|..||:..:|.|.  |..|:|.|:|...|..:||.|.:... |.
  Rat    84 LS-------HLEEDTWILWGRIANEWEEWRRRKEKLLKELIRKGIPHHFRAIVWQLLCSATD-MP 140

  Fly   675 MNDKYKILITKETKCETVIQRDIHRTFPAHKCFKEIGGSGQDALFKVSKAYAVHDSEVGYCQGLS 739
            :.::|..|:...:.||.:|:|||.||:|.|:.||.....||:.||.|.|||::.|.|||||||.:
  Rat   141 VKNQYSELLKMSSPCEKLIRRDIARTYPEHEFFKGQDSLGQEVLFNVMKAYSLVDREVGYCQGSA 205

  Fly   740 FIAASLLLHMPEEDAFCVLVALMYDYGLRDLYKAGFEVLYLRLYQLERLIKDQLPKLHEHFTACG 804
            ||...||:.||||:||||.|.||.:|.||:|:|.....|.|.:||.|.::::|||.|:.||.:..
  Rat   206 FIVGLLLMQMPEEEAFCVFVRLMQEYRLRELFKPSMAELGLCIYQFEYMLQEQLPDLNTHFRSQS 270

  Fly   805 IETHMYASQWFLTLYTARFPLCFVFHVLDVFLLDGLPVLFQVAVTLLSICESDLRQLDFEGILKY 869
            ..|.||||.|||||:...|||.....|.|:|:.:||.::|:|.:.||.:.:::|.|||.||:.:|
  Rat   271 FHTSMYASSWFLTLFLTTFPLPVATRVFDIFMYEGLEIVFRVGLALLQVNQTELMQLDMEGMSQY 335

  Fly   870 FRVTLPKKCRSSSQARKVMKQACERKI--KKLKQYEEEFLLKKQHKERLEKEAQIYENRFGEERR 932
            |:..:|.:..|...  |::.:|.:.|.  ||:|:.|:|:...|..    |.|.||...|...|.|
  Rat   336 FQRVIPHQFDSCPD--KLVLKAYQVKYNPKKMKRLEKEYAAMKSK----EMEEQIEIKRLRTENR 394

  Fly   933 KMQAEIDALNKQLTSAKERAVE------KEKKHTGIIQEYKQIIQRQ----EQDMNTLSETLGKV 987
            .::..|:.|.|:..:..:|.::      :|.:...:|:....::::|    .:|:.....|:.::
  Rat   395 LLKQRIETLEKESAALADRLIQGQVTRAQEAEENYVIKRELAVVRQQCSSTAEDLQKAQSTIRQL 459

  Fly   988 MHMVSN---CQDCQQQIDAGNDNAKSDDGKNRGQTDAMRNANEHPLGPLDPLNAA---SQRIREL 1046
            .....|   .:|....::...:.::..:.:..|   |:|...:..| .::..|::   ...:..|
  Rat   460 QEQQENPRLTEDFVSHLETELEQSRLRETETLG---ALREMQDKVL-DMEKRNSSLPDENNVARL 520

  Fly  1047 ELELAQAKLAQVEAECKNQDLNHQLSNTLSELQTNRNSWQPWLSK-----------TFNSLQEKV 1100
            :.||...|:.:.||....::|..|       ||...::||..:|:           ....||:::
  Rat   521 QEELKALKVREGEAVASARELKLQ-------LQELSDTWQAHVSRGGRWKESPRKLVLGELQDEL 578

  Fly  1101 TT 1102
            .|
  Rat   579 MT 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GAPcenA	NP_001097549.1	PTB_Rab6GAP	204..332	CDD:269922
		DUF3694	377..523	CDD:463599
		TBC	650..858	CDD:214540	91/207 (44%)
		SMC_prok_B	<876..>1087	CDD:274008	44/228 (19%)
		TPH	<883..>977	CDD:464007	23/105 (22%)
Evi5l	NP_001418968.1	TBC	117..325	CDD:214540	91/208 (44%)
		SMC_prok_B	<381..719	CDD:274008	38/211 (18%)