Protein Alignment GAPcenA and Evi5l

DIOPT Version :9

• Sequence 1: NP_001097549.1
• Gene: GAPcenA / 38945
• FlyBaseID: FBgn0035879
• Length: 1194
• Species: Drosophila melanogaster
• Sequence 2: NP_001355721.1
• Gene: Evi5l / 213027
• MGIID: 2442167
• Length: 829
• Species: Mus musculus
• Alignment Length: 587
• Identity: 175/587 - (29%)
• Similarity: 291/587 - (49%)
• Gaps: 67/587 - (11%)

  Fly   547 TEESNWKVNSIDPSEEITEQPGHQQSSSLLKMGMNNLSRIVRSSSIASIEDDCPSDYSSDGDEPL 611
            ::..|...:.::...::.||....::.|.....||...|...||.::|      |..||:
Mouse    46 SDSENLSPDELELLAKLEEQNRLLEADSKSMRSMNGSRRNSGSSLVSS------SSASSN----- 99

  Fly   612 LSGTGEVSKDCSQDTLDEWDPILREWDSEKRPKN--LAPLVRLGVPEALREKIWQKLANVEGRME 674
            ||       ...:||...|..|..||:..:|.|.  |..|:|.|:|...|..:||.|.:... |.
Mouse   100 LS-------HLEEDTWILWGRIANEWEEWRRRKEKLLKELIRKGIPHHFRAIVWQLLCSATD-MP 156

  Fly   675 MNDKYKILITKETKCETVIQRDIHRTFPAHKCFKEIGGSGQDALFKVSKAYAVHDSEVGYCQGLS 739
            :.::|..|:...:.||.:|:|||.||:|.|:.||.....||:.||.|.|||::.|.|||||||.:
Mouse   157 VKNQYSELLKMSSPCEKLIRRDIARTYPEHEFFKGQDSLGQEVLFNVMKAYSLVDREVGYCQGSA 221

  Fly   740 FIAASLLLHMPEEDAFCVLVALMYDYGLRDLYKAGFEVLYLRLYQLERLIKDQLPKLHEHFTACG 804
            ||...||:.||||:||||.|.||.:|.||:|:|.....|.|.:||.|.::::|||.|:.||.:..
Mouse   222 FIVGLLLMQMPEEEAFCVFVRLMQEYRLRELFKPSMAELGLCIYQFEYMLQEQLPDLNTHFRSQS 286

  Fly   805 IETHMYASQWFLTLYTARFPLCFVFHVLDVFLLDGLPVLFQVAVTLLSICESDLRQLDFEGILKY 869
            ..|.||||.|||||:...|||.....|.|:|:.:||.::|:|.:.||.:.:::|.|||.||:.:|
Mouse   287 FHTSMYASSWFLTLFLTTFPLPVATRVFDIFMYEGLEIVFRVGLALLQVNQTELMQLDMEGMSQY 351

  Fly   870 FRVTLPKKCRSSSQARKVMKQACERKI--KKLKQYEEEFLLKKQHKERLEKEAQIYENRFGEERR 932
            |:..:|.:..|...  |::.:|.:.|.  ||:|:.|:|:...|..    |.|.||...|...|.|
Mouse   352 FQRVIPHQFDSCPD--KLVLKAYQVKYNPKKMKRLEKEYAAMKSK----EMEEQIEIKRLRTENR 410

  Fly   933 KMQAEIDALNKQLTSAKERAVE------KEKKHTGIIQEYKQIIQRQ----EQDMNTLSETLGKV 987
            .::..|:.|.|:..:..:|.::      :|.:...:|:....::::|    .:|:.....|:.::
Mouse   411 LLKQRIETLEKESAALADRLIQGQVTRAQEAEENYVIKRELAVVRQQCSSTAEDLQKAQSTIRQL 475

  Fly   988 MHMVSN---CQDCQQQIDAGNDNAKSDDGKNRGQTDAMRNANEHPLGPLDPLNAA---SQRIREL 1046
            .....|   .:|....::...:.::..:.:..|   |:|...:..| .::..|::   ...:..|
Mouse   476 QEQQENPRLTEDFVAHLETELEQSRLRETETLG---ALREMQDKVL-DMEKRNSSLPDENNVARL 536

  Fly  1047 ELELAQAKLAQVEAECKNQDLNHQLSNTLSELQTNRNSWQPWLSK-----------TFNSLQEKV 1100
            :.||...|:.:.||....::|..|       ||...::||..||:           ....||:::
Mouse   537 QEELKALKVREGEAVASARELKLQ-------LQELSDTWQAHLSRGGRWKESPRKLVLGELQDEL 594

  Fly  1101 TT 1102
            .|
Mouse   595 MT 596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GAPcenA	NP_001097549.1	PTB_Rab6GAP	204..332	CDD:269922
		DUF3694	429..523	CDD:289256
		TBC	650..858	CDD:214540	91/207 (44%)
		Phage_Gp23	<914..991	CDD:287621	16/86 (19%)
Evi5l	NP_001355721.1	TBC	133..341	CDD:214540	91/208 (44%)
		Smc	<379..736	CDD:224117	46/233 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D191811at2759
OrthoFinder	1	1.000	-	-		FOG0000497
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920