Protein Alignment GAPcenA and Tbc1d10c

DIOPT Version :9

• Sequence 1: NP_001097549.1
• Gene: GAPcenA / 38945
• FlyBaseID: FBgn0035879
• Length: 1194
• Species: Drosophila melanogaster
• Sequence 2: NP_848765.2
• Gene: Tbc1d10c / 108995
• MGIID: 1922072
• Length: 444
• Species: Mus musculus
• Alignment Length: 457
• Identity: 112/457 - (24%)
• Similarity: 184/457 - (40%)
• Gaps: 110/457 - (24%)

  Fly   592 IASIEDDCPSDYSSDGDEPLLSG----------------TGEV-----SKDCSQDTLDEWDPILR 635
            ::.::||.    ||.|.:..|||                :||:     |.|..:....:|..:..
Mouse    10 LSELQDDS----SSLGSDSELSGPSPYRQADRYGFIGGNSGELRLCQPSADLIRQREMKWVEMTL 70

  Fly   636 EWDS--EKRPKNLAPLVRLGVPEALREKIWQKLANVEGRMEMN-DKYKILITK--ETKCETVIQR 695
            .|:.  .:|.|.:....|.|:|.|||.:.|..|.......:.| ..|:.|...  :.:....|.|
Mouse    71 HWEKTMSRRYKKVKIQCRKGIPSALRARCWPLLCGARMCQKNNPGTYQELAAAPGDPQWMETIGR 135

  Fly   696 DIHRTFPAHKCFKEIGGSGQDALFKVSKAYAVHDSEVGYCQGLSFIAASLLLHMPEEDAFCVLVA 760
            |:||.||.|:.|....|.||..|.:|.|||.::..|.||||....:||.||:|:|.|:||..||.
Mouse   136 DLHRQFPLHEMFVSPQGHGQQGLLQVLKAYTLYRPEQGYCQAQGPVAAVLLMHLPPEEAFWCLVQ 200

  Fly   761 LMYDYGLRDLYKAGFEVLYLRLYQLE-----RLIKDQLPKLHEHFTACGIETHMYASQWFLTLYT 820
            :.      ::|..|:...::...||:     .|::.|||::::|....|:...:|..:|||.|:|
Mouse   201 IC------EVYLPGYYGPHMEAVQLDAEVFMALLRRQLPRVYKHLQQVGVGPLLYLPEWFLCLFT 259

  Fly   821 ARFPLCFVFHVLDVFLLDGLPVLFQVAVTLLSICESDLRQLDFEGILKYFRVTLPKKCRSSSQAR 885
            ...|...|..:.|.||.:|..|||:|.:||:.:....:.|
Mouse   260 RSLPFPTVLRIWDAFLSEGAKVLFRVGLTLMRLALGTVEQ------------------------- 299

  Fly   886 KVMKQACERKIKKL--------KQYEEEFLLKKQHKERLEKEAQIYENRFGEERRKMQAEIDALN 942
               :.||...::.|        .|.:||..:.:.|...|.:             |.:|.||....
Mouse   300 ---RTACPGLLETLGALRAIPPTQLQEEVFMSQVHSVTLSE-------------RVLQQEIRIQL 348

  Fly   943 KQLTSA-------------KERAVEKEKKHTGIIQEYKQIIQR-------QEQDMNTLSETLGKV 987
            .||:.:             ..:|:.:.::..|:.:..|..|.|       :.:......:|.||.
Mouse   349 AQLSKSLPGPAPLPQARLPGAQAIFESQQLAGVRESTKPEIPRIVVQPPEEPKPPRRKPQTRGKT 413

  Fly   988 MH 989
            .|
Mouse   414 FH 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GAPcenA	NP_001097549.1	PTB_Rab6GAP	204..332	CDD:269922
		DUF3694	429..523	CDD:289256
		TBC	650..858	CDD:214540	72/215 (33%)
		Phage_Gp23	<914..991	CDD:287621	16/96 (17%)
Tbc1d10c	NP_848765.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..32		8/25 (32%)
		TBC	87..292	CDD:214540	72/210 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	383..444		7/33 (21%)
		Interaction with calcineurin. /evidence=ECO:0000250	404..444		4/12 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910