Protein Alignment GAPcenA and TBC1D3D

DIOPT Version :9

• Sequence 1: NP_001097549.1
• Gene: GAPcenA / 38945
• FlyBaseID: FBgn0035879
• Length: 1194
• Species: Drosophila melanogaster
• Sequence 2: XP_006722311.1
• Gene: TBC1D3D / 101060389
• HGNCID: 28944
• Length: 610
• Species: Homo sapiens
• Alignment Length: 390
• Identity: 93/390 - (23%)
• Similarity: 155/390 - (39%)
• Gaps: 85/390 - (21%)

  Fly   555 NSID--------PSEEITEQPGHQQSSSLLKMGMNNLSRIVRSS-------SIASIEDDCPSD-- 602
            |::|        ||.|...|.|......:...|::......|:|       .:..::..|.|.
Human    44 NNVDHLGIVQSCPSWESAPQEGPCPPFPVPSPGLSPELERDRASPFWGSAPRLGPLQAPCSSSAL 108

  Fly   603 ----YSSDGDEPLLSGTG-EVSKDCSQDTLDEWDPILREWDSEKRPKNLAPLVRLGVPEALREKI 662
                ||.....||.:... ::.::.|:.:  :|..:|.:|:..|..:.|......|:|..:|..:
Human   109 PGLPYSETELPPLTAREAKQIRREISRKS--KWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPM 171

  Fly   663 WQKLANVEGRMEMND--KYKILITKETKCETVIQ---RDIHRTFPAHKCFKEIGGSGQDALFKVS 722
            |..|.|.| .|::.:  :|:|:..|..:....||   ||:..|...|..|::..|:.|..|..:.
Human   172 WSVLLNTE-EMKLKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHIL 235

  Fly   723 KAYAVHDSEVGYCQGLSFIAASLLLHMPEEDAFCVLVALMYD----------------YGLRDLY 771
            .||..::.|||||:.||.|||..||::||||||..||.|:..                .||:|
Human   236 LAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQD-- 298

  Fly   772 KAGFEVLYLRLYQLERLIKDQLPKLHEH---FTACGIETHMYASQWFLTLYTARFPLCFVFHVLD 833
                        |.|.::....||...|   ...||..:.:..   .:.:......|.....:.|
Human   299 ------------QQEHVVATSQPKTMGHQDKKDLCGQCSPLGC---LIRILIDGISLGLTLRLWD 348

  Fly   834 VFLLDG----LPV------LFQVAVTLLSICES---------DLRQLDFEGILKYFRVTLPKKCR 879
            |:|::|    :|:      :.|..:|..|.|..         |....|.:.:||:.|.::.|..|
Human   349 VYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTR 413

  Fly   880  879
            Human   414  413

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GAPcenA	NP_001097549.1	PTB_Rab6GAP	204..332	CDD:269922
		DUF3694	429..523	CDD:289256
		TBC	650..858	CDD:214540	64/250 (26%)
		Phage_Gp23	<914..991	CDD:287621
TBC1D3D	XP_006722311.1	TBC	160..373	CDD:214540	61/230 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810