Protein Alignment GAPcenA and sgsm1b

DIOPT Version :10

• Sequence 1: NP_001097549.1
• Gene: GAPcenA / 38945
• FlyBaseID: FBgn0035879
• Length: 1194
• Species: Drosophila melanogaster
• Sequence 2: XP_073770421.1
• Gene: sgsm1b / 100535556
• ZFINID: ZDB-GENE-091117-39
• Length: 1497
• Species: Danio rerio
• Alignment Length: 997
• Identity: 200/997 - (20%)
• Similarity: 356/997 - (35%)
• Gaps: 269/997 - (26%)

  Fly     2 DDNLSTKSSESSITT----SGEYEIVTDSN----VASPMEQVKQVVNQ-----EGTQPEVGGKPP 53
            |..:||.||:||.:.    :|.:   :|||    |...:::|..:.::     |..||::    |
Zfish   629 DSTISTDSSQSSNSDKQSHAGSH---SDSNSSTQVFGSVDEVDPIESEPKPKDEKPQPKI----P 686

  Fly    54 TSLSALALSSPEAG-------------GDRSPTLDMAHNRNLSDMQHEMTDALKDLELERGVAAS 105
            ........|||::|             .|.||:.:....:.....|.::.:..|:.:.|......
Zfish   687 NGALPNCTSSPDSGHPSSRNFSVTSAMSDCSPSTEETSTQESKGNQPDIEEKPKEEQPENSSTTQ 751

  Fly   106 GEKSAQRLPSHQQKSLTLPLTGSGGGSV-DPEMRFPCTLFTPKSEETLDDASSSNRVGHSVFYDC 169
            ....|.....::.|..|...:.:....: |...:.|..|..||.:|.  :|.:..|  .|....|
Zfish   752 NTDKAAITTQNKSKLQTSETSRAETDQIKDAISKNPTNLSEPKEDEV--NAGAETR--KSEVNKC 812

  Fly   170 -IDASPACVEEKQDAMKPEKGDTTDEEVSEIDQGC------TIFSGVTYLGAANINAPKSETEVY 227
             :..|....||.:.:...:..|.....:|.:|:..      .|...|.....:..:||:|..|..
Zfish   813 EVQPSRDPAEESRSSESKQAEDADPVSLSIVDEDTKSNTEQEIGLKVNEDSKSQQSAPESTPEDV 877

  Fly   228 RIMGELNSGS---KSVGLKIT------VSIP-NCSEGLVVLHD--AESNTIIATYEISSIILYYR 280
            :....|:|.|   :...||::      .|.| :.||.:....:  :||||
Zfish   878 KTSQNLSSESNTKQETSLKVSEDSKCQPSAPESTSEAMTTSQNLSSESNT--------------- 927

  Fly   281 GPVDTVENGCFAFTWLHGDALFQCHVFRCHIPEAVNQVSACFQKAFQTYPPSMSCSLNSAVDMAN 345
                ..|.|.                       .||:.|.|...|.::....|..|.|.:   :.
Zfish   928 ----EQETGL-----------------------KVNEDSKCQPSAPESTSEDMKTSQNIS---SE 962

  Fly   346 SVTSDVSGNPLNTAGYEFIVSLEIRERVAKNSYAAVPRDRGCFKLRANTDKEVCITVKQTPSNVL 410
            |.|...:|..:|              :.:|:..:| |:         :|.:.:     :|..|:|
Zfish   963 SNTEQETGLKVN--------------KDSKSEQSA-PK---------STPEHM-----KTSQNLL 998

  Fly   411 QPLHIERCFGVLV---------APGKL-VVQKDMHLIDMHSMGYIQPGGTGVATESDSNAQQSSS 465
            ..|::|:..|:.|         ||... ...|....|...|....:   ||:....||.::||:
Zfish   999 SELNMEQATGLKVNEDSKCQPSAPESTPEAMKTSQNISSESNTQQE---TGLKVNKDSKSEQSA- 1059

  Fly   466 WPYTIRAEWKAQEKAFEQLNLESSKTNLTVAVDIV------------MRRIQE----PVRFVIET 514
             |.:.....|..:....:||:|.: |.|.|..|..            |:..|.    |.......
Zfish  1060 -PKSTPEHMKTSQNLLSELNMEQA-TGLKVNEDSKCQPSAPESTLDDMKTSQNLSSGPQNVPQTA 1122

  Fly   515 PVTIQSASEMRIMDHFMSK---RPMTLRFYLHLKRTEESNWKVNSID-PSEEITEQPGHQQSSSL 575
            |.||...||     |..::   :.||       :...||...:.|:. ||.::::     .|.|.
Zfish  1123 PQTISWDSE-----HNRARSIIKQMT-------ESESESCGPLTSLSKPSPDMSD-----DSPSA 1170

  Fly   576 LKMGMNNLSRIVRSSSIASIEDDCPSDYS---------SDGDE-PLLSGTGEVSKDCSQDTLDE- 629
            |:| ....|.:|..||..|:   |.:..:         :.|:: |:.....|:..:...:|..|
Zfish  1171 LEM-EEIPSSVVYMSSETSM---CRTPLTLARPVAPCIAAGEKSPMGMPALELCMEPGVNTTPEG 1231

  Fly   630 WDPILREWDSEKRPK--NLAPLVRLGVPEAL-----REKIWQKLANV--EGRMEMNDKYKILITK 685
            .|..|    ||:.|:  ||.|     .|::|     :..|...::::  ....|:.|.|.:.:.:
Zfish  1232 TDSAL----SEEEPEMDNLFP-----KPDSLAVTGDKNDIASPVSSIGTTYSQELVDLYTLNLHR 1287

  Fly   686 ETKCETVIQRDIHRTFPAHKCFKEIGGSGQDALFKVSKAYAVHDSEVGYCQGLSFIAASLLLHMP 750
                   |.:|:.|....:..|..   :..:.|..:..:|.....::||.||:..:.|.||:.:.
Zfish  1288 -------IDKDVQRCDRNYWYFTP---ANLEKLRNIMCSYVWQHLDIGYVQGMCDLLAPLLVILD 1342

  Fly   751 EED-AFCVLVALMYDYGLRDLYKAGFEVLYLRLYQLERLIKDQLPKLHEHFTACGIETHMY-ASQ 813
            :|. ||.....||........:....:..:..:..|.:::..:|.:|.:.   .|..||.| ..:
Zfish  1343 DEAMAFSCFTELMKRMNQNFPHGGAMDTHFANMRSLIQILDSELFELMQQ---NGDYTHFYFCYR 1404

  Fly   814 WFL-----------------TLYTARFPLCFVFHVLDVFLLDGLPVLFQVAVTLLSICESDL--R 859
            |||                 |::.||:.....|            ||| :|:.|:.:....:  .
Zfish  1405 WFLLDFKREMVYDDVFSVWETIWAARYASSEHF------------VLF-IALALVELYRDIILEN 1456

  Fly   860 QLDFEGILKYF-----RVTLPK 876
            .:||..|:|:|     |..:||
Zfish  1457 NMDFTDIIKFFNEMAERHDVPK 1478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GAPcenA	NP_001097549.1	PTB_Rab6GAP	204..332	CDD:269922	26/139 (19%)
		DUF3694	377..523	CDD:463599	36/171 (21%)
		TBC	650..858	CDD:214540	43/233 (18%)
		SMC_prok_B	<876..>1087	CDD:274008	1/1 (100%)
		TPH	<883..>977	CDD:464007
sgsm1b	XP_073770421.1	None