DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7182 and SSA4

DIOPT Version :9

Sequence 1:	NP_001286979.1	Gene:	CG7182 / 38944	FlyBaseID:	FBgn0035878	Length:	513	Species:	Drosophila melanogaster
Sequence 2:	NP_011029.3	Gene:	SSA4 / 856840	SGDID:	S000000905	Length:	642	Species:	Saccharomyces cerevisiae

Alignment Length:	516	Identity:	143/516 - (27%)
Similarity:	243/516 - (47%)	Gaps:	65/516 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 GIKIGNSTLCIAHVRADGKAEVIANKQGDRVSQACLLWDGASEIECGLTAKQKMANRPRQAVAHS 70
            ||.:|.:..|:||. |:.:.|:|||.||:|.:.:.:.:.....: .|..||.:.|..|...|..:
Yeast     6 GIDLGTTYSCVAHF-ANDRVEIIANDQGNRTTPSYVAFTDTERL-IGDAAKNQAAMNPHNTVFDA 68

  Fly    71 FQLLQPKEELTEEKLSSALREIPCDFDKEELVFRMEHTVPSDREDQDDRVV--------TKDLSA 127
            .:|:..|                  ||..|:....:| .|....|:..:.|        ||..:.
Yeast    69 KRLIGRK------------------FDDPEVTNDAKH-YPFKVIDKGGKPVVQVEYKGETKTFTP 114

  Fly   128 YQVTVELLRAELELAHQYHTDGEQAPIAVLSIPSYYPASAYKLLADAAQTAGFHVAQIITEPTAA 192
            .:::..:|....|.|..:.  |.:...||:::|:|:..|..:...||...||.:|.:||.|||||
Yeast   115 EEISSMILTKMKETAENFL--GTEVKDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAA 177

  Fly   193 VLGYSIGEEQTEQRRHVLTIKCGGLYSDIAFYSVQNGLFVQLATFGPFPIGGRQFTEALVQFICE 257
            .:.|.: ::::::..:||....||...|::..|:..|:|...||.|...:||..|...||.|:.|
Yeast   178 AIAYGL-DKKSQKEHNVLIFDLGGGTFDVSLLSIDEGVFEVKATAGDTHLGGEDFDSRLVNFLAE 241

  Fly   258 EFRRKYKLDPHESRRSVAKIRTAAANCKHILTTMPSTQLYIDSLMDGVDYNAQMSRARFESLIQP 322
            ||:||.|.|...::||:.::||||...|..|::...|.:.||||.:|:|:...::|||||.|...
Yeast   242 EFKRKNKKDLTTNQRSLRRLRTAAERAKRTLSSSAQTSIEIDSLFEGIDFYTSITRARFEELCAD 306

  Fly   323 VINNLIQQLGECVEQAQKEHPGLSKIDDIVLLGATMQIPKLQAAVGARFPDAKLHNSHSADEVVA 387
            :..:.::.:.:.:..::.:.   |:||:|||:|.:.:|||:|..|...|...:.:.|.:.||.||
Yeast   307 LFRSTLEPVEKVLADSKLDK---SQIDEIVLVGGSTRIPKVQKLVSDFFNGKEPNRSINPDEAVA 368

  Fly   388 IGCARQAVCLIDPLEQQLHKEEDCVVAEDDLFIWHGNDESNAKLVLG-------------RGSVL 439
            .|.|.||..|..   .|....:|.::.:            .|.|.||             |.|.:
Yeast   369 YGAAVQAAILTG---DQSSTTQDLLLLD------------VAPLSLGIETAGGIMTKLIPRNSTI 418

  Fly   440 PAKIRISLPQSEEGKGDDVSKAAASFKLRTGESEILARLPDSTIP--EDGLYQLEVEVDVD 498
            |.|.........:.:...:.:.....:.||.::.:|.:...|.||  ..|:.|:||..|:|
Yeast   419 PTKKSEVFSTYADNQPGVLIQVFEGERTRTKDNNLLGKFELSGIPPAPRGVPQIEVTFDID 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7182	NP_001286979.1	NBD_sugar-kinase_HSP70_actin	5..394	CDD:302596	118/395 (30%)
SSA4	NP_011029.3	PTZ00009	4..642	CDD:240227	143/516 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810