DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7182 and SSE1

DIOPT Version :9

Sequence 1:	NP_001286979.1	Gene:	CG7182 / 38944	FlyBaseID:	FBgn0035878	Length:	513	Species:	Drosophila melanogaster
Sequence 2:	NP_015219.1	Gene:	SSE1 / 855998	SGDID:	S000006027	Length:	693	Species:	Saccharomyces cerevisiae

Alignment Length:	531	Identity:	129/531 - (24%)
Similarity:	234/531 - (44%)	Gaps:	74/531 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 FGIKIGNSTLCIAHVRADGKAEVIANKQGDRVSQACLLWDGASEIECGLTAKQKMANRPRQAVAH 69
            ||:.:||:...:|..|..| .:::.|:..:| |...::..|......|.|.|.|..:..:..||:
Yeast     5 FGLDLGNNNSVLAVARNRG-IDIVVNEVSNR-STPSVVGFGPKNRYLGETGKNKQTSNIKNTVAN 67

  Fly    70 SFQLL-----QPKEELTEEKLSSALREIPCDFDKE---ELVFRMEHTVPSDRE------DQDDRV 120
            ..:::     .|..|...:..:|.|.|:.   ||:   |:.|..|..|.|..:      |:....
Yeast    68 LKRIIGLDYHHPDFEQESKHFTSKLVELD---DKKTGAEVRFAGEKHVFSATQLAAMFIDKVKDT 129

  Fly   121 VTKDLSAYQVTVELLRAELELAHQYHTDGEQAPIAVLSIPSYYPASAYKLLADAAQTAGFHVAQI 185
            |.:|..|....|                       .:::|.:|.......:||||:.||.:..:|
Yeast   130 VKQDTKANITDV-----------------------CIAVPPWYTEEQRYNIADAARIAGLNPVRI 171

  Fly   186 ITEPTAAVLGYSIGE----EQTEQRRHVLTIKCGGLYSDIAFYSVQNGLFVQLATFGPFPIGGRQ 246
            :.:.|||.:.|.|.:    |..|:.|.|..:..|......:..:.:.|....|.|......|||.
Yeast   172 VNDVTAAGVSYGIFKTDLPEGEEKPRIVAFVDIGHSSYTCSIMAFKKGQLKVLGTACDKHFGGRD 236

  Fly   247 FTEALVQFICEEFRRKYKLDPHESRRSVAKIRTAAANCKHILTTMPSTQLYIDSLMDGVDYNAQM 311
            |..|:.:...:||:.|||:|..|:.::..:|.|||...|.:|:...:....::|:|:.||.::|:
Yeast   237 FDLAITEHFADEFKTKYKIDIRENPKAYNRILTAAEKLKKVLSANTNAPFSVESVMNDVDVSSQL 301

  Fly   312 SRARFESLIQPVINNLIQQLGECVEQAQKEHPGLSKIDDIVLLGATMQIPKLQAAVGARFPDAKL 376
            ||...|.|::|::..:.:.:.:.:.||:.   ...::|.:.::|.|.:||.|:.::...| ...|
Yeast   302 SREELEELVKPLLERVTEPVTKALAQAKL---SAEEVDFVEIIGGTTRIPTLKQSISEAF-GKPL 362

  Fly   377 HNSHSADEVVAIGCARQAVCLI--DPLEQQLHKEEDCVVAEDDLFIW--HGNDESNAKLVLGRGS 437
            ..:.:.||.:|.|.|  .:|.|  ..|..:..|.|| :......:.|  ...||.:.: |...||
Yeast   363 STTLNQDEAIAKGAA--FICAIHSPTLRVRPFKFED-IHPYSVSYSWDKQVEDEDHME-VFPAGS 423

  Fly   438 VLPAKIRISLPQSEEGKGDDVSKAAASFKLRTGESEILARLPDSTIPEDGLYQLEVE-VDVDDKD 501
            ..|:...|:|.::    ||        |.:....::| .:||.:| ||. :...|:. |.:.:..
Yeast   424 SFPSTKLITLNRT----GD--------FSMAASYTDI-TQLPPNT-PEQ-IANWEITGVQLPEGQ 473

  Fly   502 GNVVPLVRLRC 512
            .:|...::|||
Yeast   474 DSVPVKLKLRC 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7182	NP_001286979.1	NBD_sugar-kinase_HSP70_actin	5..394	CDD:302596	99/406 (24%)
SSE1	NP_015219.1	HSP70	4..644	CDD:394970	129/531 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900