DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7182 and SSC1

DIOPT Version :9

Sequence 1:	NP_001286979.1	Gene:	CG7182 / 38944	FlyBaseID:	FBgn0035878	Length:	513	Species:	Drosophila melanogaster
Sequence 2:	NP_012579.1	Gene:	SSC1 / 853503	SGDID:	S000003806	Length:	654	Species:	Saccharomyces cerevisiae

Alignment Length:	543	Identity:	135/543 - (24%)
Similarity:	232/543 - (42%)	Gaps:	117/543 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 GIKIGNSTLCIAHVRADGKA-EVIANKQGDRVSQACLLWDGASEIECGLTAKQKMANRPRQAVAH 69
            ||.:|.:...:|.:  :||. ::|.|.:|.|.:.:.:.:....|...|:.||::....|...:..
Yeast    34 GIDLGTTNSAVAIM--EGKVPKIIENAEGSRTTPSVVAFTKEGERLVGIPAKRQAVVNPENTLFA 96

  Fly    70 SFQLLQPKEELTEEKLSSALREIPCDFDKEELVFRMEHTVPSDREDQDDRVVT---KDLSAYQVT 131
            :.:|:..:.|  :.::...::::|....|               ....|..|.   :..|..|:.
Yeast    97 TKRLIGRRFE--DAEVQRDIKQVPYKIVK---------------HSNGDAWVEARGQTYSPAQIG 144

  Fly   132 VELLRAELELAHQYHTDGEQAPIAVLSIPSYYPASAYKLLADAAQTAGFHVAQIITEPTAAVLGY 196
            ..:|....|.|..|.  |:....||:::|:|:..|..:...||.|..|.:|.:::.|||||.|.|
Yeast   145 GFVLNKMKETAEAYL--GKPVKNAVVTVPAYFNDSQRQATKDAGQIVGLNVLRVVNEPTAAALAY 207

  Fly   197 SIGEEQTEQRRHVLTIKCGGLYSDIAFYSVQNGLFVQLATFGPFPIGGRQFTEALVQFICEEFRR 261
              |.|:::. :.|.....||...||:...:.||:|...:|.|...:||..|...|::.|...|:.
Yeast   208 --GLEKSDS-KVVAVFDLGGGTFDISILDIDNGVFEVKSTNGDTHLGGEDFDIYLLREIVSRFKT 269

  Fly   262 KYKLDPHESRRSVAKIRTAAANCKHILTTMPSTQL---YIDSLMDGVDY-NAQMSRARFESLIQP 322
            :..:|....|.::.:||.||...|..|::..||::   :|.:...|..: |.:.|||:||:|..|
Yeast   270 ETGIDLENDRMAIQRIREAAEKAKIELSSTVSTEINLPFITADASGPKHINMKFSRAQFETLTAP 334

  Fly   323 VINNLIQQLGECVEQAQKEHPGL--SKIDDIVLLGATMQIPKLQAAVGARF---PDAKLHNSHSA 382
            ::...:..:.:.::.|     ||  |.|.:::|:|...::||:...|.:.|   |...:    :.
Yeast   335 LVKRTVDPVKKALKDA-----GLSTSDISEVLLVGGMSRMPKVVETVKSLFGKDPSKAV----NP 390

  Fly   383 DEVVAIGCARQA---------VCLIDPLEQQLHKEEDCVVAEDDLFIWHGNDESNAKLVLG---- 434
            ||.||||.|.|.         |.|:|.....|..|                       .||
Yeast   391 DEAVAIGAAVQGAVLSGEVTDVLLLDVTPLSLGIE-----------------------TLGGVFT 432

  Fly   435 ----RGSVLPAKIRISLPQSEEGKGDDVSKAAA---SFKLRT--GESEI-----------LARLP 479
                |.:.:|.|           |....|.|||   |.::|.  ||.|:           ||.:|
Yeast   433 RLIPRNTTIPTK-----------KSQIFSTAAAGQTSVEIRVFQGERELVRDNKLIGNFTLAGIP 486

  Fly   480 DSTIPEDGLYQLEVEVDVDDKDG 502
            .:  |: |:.|:||..|: |.||
Yeast   487 PA--PK-GVPQIEVTFDI-DADG 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7182	NP_001286979.1	NBD_sugar-kinase_HSP70_actin	5..394	CDD:302596	102/400 (26%)
SSC1	NP_012579.1	dnaK	30..633	CDD:234715	135/543 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900