DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7182 and SSA3

DIOPT Version :9

Sequence 1:	NP_001286979.1	Gene:	CG7182 / 38944	FlyBaseID:	FBgn0035878	Length:	513	Species:	Drosophila melanogaster
Sequence 2:	NP_009478.1	Gene:	SSA3 / 852203	SGDID:	S000000171	Length:	649	Species:	Saccharomyces cerevisiae

Alignment Length:	516	Identity:	142/516 - (27%)
Similarity:	239/516 - (46%)	Gaps:	65/516 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 GIKIGNSTLCIAHVRADGKAEVIANKQGDRVSQACLLWDGASEIECGLTAKQKMANRPRQAVAHS 70
            ||.:|.:..|:||...| :.|:|||.||:|.:.:.:.:.....: .|..||.:.|..|...|..:
Yeast     6 GIDLGTTYSCVAHFSND-RVEIIANDQGNRTTPSYVAFTDTERL-IGDAAKNQAAINPHNTVFDA 68

  Fly    71 FQLLQPKEELTEEKLSSALREIPCDFDKEELVFRMEHTVPSDREDQDDRVV--------TKDLSA 127
            .:|:..|                  ||..|:....:| .|.....:|.:.|        ||..:.
Yeast    69 KRLIGRK------------------FDDPEVTTDAKH-FPFKVISRDGKPVVQVEYKGETKTFTP 114

  Fly   128 YQVTVELLRAELELAHQYHTDGEQAPIAVLSIPSYYPASAYKLLADAAQTAGFHVAQIITEPTAA 192
            .:::..:|....|.|..|.  |.....||:::|:|:..|..:...||...||.:|.:||.|||||
Yeast   115 EEISSMVLSKMKETAENYL--GTTVNDAVVTVPAYFNDSQRQATKDAGTIAGMNVLRIINEPTAA 177

  Fly   193 VLGYSIGEEQTEQRRHVLTIKCGGLYSDIAFYSVQNGLFVQLATFGPFPIGGRQFTEALVQFICE 257
            .:.|.: :::.....:||....||...|::..|:..|:|...||.|...:||..|...||..:..
Yeast   178 AIAYGL-DKKGRAEHNVLIFDLGGGTFDVSLLSIDEGVFEVKATAGDTHLGGEDFDNRLVNHLAT 241

  Fly   258 EFRRKYKLDPHESRRSVAKIRTAAANCKHILTTMPSTQLYIDSLMDGVDYNAQMSRARFESLIQP 322
            ||:||.|.|...::||:.::||||...|..|::...|.:.||||.:|:|:...::|||||.|...
Yeast   242 EFKRKTKKDISNNQRSLRRLRTAAERAKRALSSSSQTSIEIDSLFEGMDFYTSLTRARFEELCAD 306

  Fly   323 VINNLIQQLGECVEQAQKEHPGLSKIDDIVLLGATMQIPKLQAAVGARFPDAKLHNSHSADEVVA 387
            :..:.::.:.:.::.::.:.   |:||:|||:|.:.:|||:|..|...|...:.:.|.:.||.||
Yeast   307 LFRSTLEPVEKVLKDSKLDK---SQIDEIVLVGGSTRIPKIQKLVSDFFNGKEPNRSINPDEAVA 368

  Fly   388 IGCARQAVCLIDPLEQQLHKEEDCVVAEDDLFIWHGNDESNAKLVLG-------------RGSVL 439
            .|.|.||..|..   .|..|.:|.::.:            .|.|.||             |.|.:
Yeast   369 YGAAVQAAILTG---DQSTKTQDLLLLD------------VAPLSLGIETAGGIMTKLIPRNSTI 418

  Fly   440 PAKIRISLPQSEEGKGDDVSKAAASFKLRTGESEILARLPDSTIP--EDGLYQLEVEVDVD 498
            |.|...:.....:.:...:.:.....:.||.::.:|.:...|.||  ..|:.|::|..|:|
Yeast   419 PTKKSETFSTYADNQPGVLIQVFEGERTRTKDNNLLGKFELSGIPPAPRGVPQIDVTFDID 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7182	NP_001286979.1	NBD_sugar-kinase_HSP70_actin	5..394	CDD:302596	117/395 (30%)
SSA3	NP_009478.1	PTZ00009	4..649	CDD:240227	142/516 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S779
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.760