DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7182 and SSA2

DIOPT Version :9

Sequence 1:	NP_001286979.1	Gene:	CG7182 / 38944	FlyBaseID:	FBgn0035878	Length:	513	Species:	Drosophila melanogaster
Sequence 2:	NP_013076.1	Gene:	SSA2 / 850636	SGDID:	S000003947	Length:	639	Species:	Saccharomyces cerevisiae

Alignment Length:	531	Identity:	147/531 - (27%)
Similarity:	243/531 - (45%)	Gaps:	96/531 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 GIKIGNSTLCIAHVRADGKAEVIANKQGDRVSQACLLWDGASEIE--CGLTAKQKMANRPRQAVA 68
            ||.:|.:..|:||...| :.::|||.||:|.:.:.:   |.::.|  .|..||.:.|..|...|
Yeast     6 GIDLGTTYSCVAHFSND-RVDIIANDQGNRTTPSFV---GFTDTERLIGDAAKNQAAMNPANTV- 65

  Fly    69 HSFQLLQPKEELTEEKLSSALREIPCDFDKEELVFRMEH----TVPSDREDQ---DDRVVTKDLS 126
                             ..|.|.|..:|:..|:...|:|    .:..|.:.|   :.:..||:.:
Yeast    66 -----------------FDAKRLIGRNFNDPEVQGDMKHFPFKLIDVDGKPQIQVEFKGETKNFT 113

  Fly   127 AYQVTVELLRAELELAHQYHTDGEQAPIAVLSIPSYYPASAYKLLADAAQTAGFHVAQIITEPTA 191
            ..|::..:|....|.|..|.  |.:...||:::|:|:..|..:...||...||.:|.:||.||||
Yeast   114 PEQISSMVLGKMKETAESYL--GAKVNDAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTA 176

  Fly   192 AVLGYSIGEEQTEQRRHVLTIKCGGLYSDIAFYSVQNGLFVQLATFGPFPIGGRQFTEALVQFIC 256
            |.:.|.:.::..|:  |||....||...|::..|:::|:|...||.|...:||..|...||....
Yeast   177 AAIAYGLDKKGKEE--HVLIFDLGGGTFDVSLLSIEDGIFEVKATAGDTHLGGEDFDNRLVNHFI 239

  Fly   257 EEFRRKYKLDPHESRRSVAKIRTAAANCKHILTTMPSTQLYIDSLMDGVDYNAQMSRARFESLIQ 321
            :||:||.|.|...::|::.::|||....|..|::...|.:.||||.:|:|:...::|||||.|..
Yeast   240 QEFKRKNKKDLSTNQRALRRLRTACERAKRTLSSSAQTSVEIDSLFEGIDFYTSITRARFEELCA 304

  Fly   322 PVINNLIQQLGECVEQAQKEHPGLSKIDDIVLLGATMQIPKLQAAVGARFPDAKLHNSHSADEVV 386
            .:..:.:..:.:.:..|:.:.   |::|:|||:|.:.:|||:|..|...|...:.:.|.:.||.|
Yeast   305 DLFRSTLDPVEKVLRDAKLDK---SQVDEIVLVGGSTRIPKVQKLVTDYFNGKEPNRSINPDEAV 366

  Fly   387 AIGCARQAVCLIDPLEQQLHKEEDCVVAEDDLFIWHGNDESNAKLVLG-------------RGSV 438
            |.|.|.||..|..   .:..|.:|.::.:            .|.|.||             |.|.
Yeast   367 AYGAAVQAAILTG---DESSKTQDLLLLD------------VAPLSLGIETAGGVMTKLIPRNST 416

  Fly   439 LPAK--------------IRISLPQSEEGKGDDVSKAAASFKLRTGESEILARLPDSTIP--EDG 487
            :|.|              :.|.:.:.|..|              |.::.:|.:...|.||  ..|
Yeast   417 IPTKKSEVFSTYADNQPGVLIQVFEGERAK--------------TKDNNLLGKFELSGIPPAPRG 467

  Fly   488 LYQLEVEVDVD 498
            :.|:||..|||
Yeast   468 VPQIEVTFDVD 478

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7182	NP_001286979.1	NBD_sugar-kinase_HSP70_actin	5..394	CDD:302596	119/396 (30%)
SSA2	NP_013076.1	PTZ00009	4..639	CDD:240227	147/531 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810