DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7182 and ERD2

DIOPT Version :9

Sequence 1:	NP_001286979.1	Gene:	CG7182 / 38944	FlyBaseID:	FBgn0035878	Length:	513	Species:	Drosophila melanogaster
Sequence 2:	NP_176036.1	Gene:	ERD2 / 842094	AraportID:	AT1G56410	Length:	617	Species:	Arabidopsis thaliana

Alignment Length:	537	Identity:	135/537 - (25%)
Similarity:	235/537 - (43%)	Gaps:	98/537 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 PRFGIKIGNSTLCIAHVRADGKAEVIANKQGDRVSQACLLWDGASEIECGLTAKQKMANRPRQAV 67
            |..||.:|.:..|:...:.| :.|:|||.||:|.:.:.:.:.. ||...|..||.::|..|...|
plant     8 PAIGIDLGTTYSCVGVWQHD-RVEIIANDQGNRTTPSYVAFTD-SERLIGDAAKNQVAMNPVNTV 70

  Fly    68 AHSFQLLQPKEELTEEKLSSALREIPCDFDKEELVFR--MEHTVPSDRE--------DQDDRVV- 121
                                        ||.:.|:.|  .:.:|.||.:        .|.|:.:
plant    71 ----------------------------FDAKRLIGRRFSDASVQSDMKFWPFKVTPGQADKPMI 107

  Fly   122 -------TKDLSAYQVTVELLRAELELAHQYHTDGEQAPIAVLSIPSYYPASAYKLLADAAQTAG 179
                   .|..:|.:::..:|....|:|..|.  |.....||:::|:|:..|..:...||...||
plant   108 FVNYKGEEKQFAAEEISSMVLIKMREIAEAYL--GSSIKNAVVTVPAYFNDSQRQATKDAGVIAG 170

  Fly   180 FHVAQIITEPTAAVLGYSIGEEQTEQR-RHVLTIKCGGLYSDIAFYSVQNGLFVQLATFGPFPIG 243
            .:|.:||.|||||.:.|.:.::.|... ::||....||...|::..:::.|:|...||.|...:|
plant   171 LNVLRIINEPTAAAIAYGLDKKATSVGIKNVLIFDLGGGTFDVSLLTIEEGIFEVKATAGDTHLG 235

  Fly   244 GRQFTEALVQFICEEFRRKYKLDPHESRRSVAKIRTAAANCKHILTTMPSTQLYIDSLMDGVDYN 308
            |..|...:|....:||:||.|.|.....|::.::|||....|..|::...|.:.:|||.:|:|:.
plant   236 GEDFDNRMVNHFVQEFKRKNKKDISGDARALRRLRTACERAKRTLSSTAQTTVEVDSLFEGIDFY 300

  Fly   309 AQMSRARFESLIQPVINNLIQQLGECVEQAQKEHPGLSKIDDIVLLGATMQIPKLQAAVGARFPD 373
            :.::||:||.:...:....::.:.:|:..::.:.   |.:.|:||:|.:.:|||:|..:...|..
plant   301 SPITRAKFEEMNMDLFRKCMEPVMKCLRDSKMDK---SMVHDVVLVGGSTRIPKVQQLLQDFFNG 362

  Fly   374 AKLHNSHSADEVVAIGCARQAVCLIDPLEQQLHKEEDCVVAEDDLFIWHGNDESNAKLVLG---- 434
            .:|..|.:.||.||.|.|.||..|..                      .||::....|:|.
plant   363 KELCKSINPDEAVAYGAAVQAAILSG----------------------EGNEKVQDLLLLDVTPL 405

  Fly   435 ----------------RGSVLPAKIRISLPQSEEGKGDDVSKAAASFKLRTGESEILARLPDSTI 483
                            |.:.:|||.......:.:.:.|.:.:.....:.||.::.||.:...|.|
plant   406 SLGIETIGGVMTTLIQRNTTIPAKKEQEFTTTVDNQPDVLIQVYEGERARTIDNNILGQFVLSGI 470

  Fly   484 P--EDGLYQLEVEVDVD 498
            |  ..|:.|..|..|:|
plant   471 PPAPRGIPQFTVCFDID 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7182	NP_001286979.1	NBD_sugar-kinase_HSP70_actin	5..394	CDD:302596	110/407 (27%)
ERD2	NP_176036.1	PTZ00009	5..617	CDD:240227	135/537 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810