DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7182 and hspa14

DIOPT Version :9

Sequence 1:	NP_001286979.1	Gene:	CG7182 / 38944	FlyBaseID:	FBgn0035878	Length:	513	Species:	Drosophila melanogaster
Sequence 2:	NP_001038541.1	Gene:	hspa14 / 565232	ZFINID:	ZDB-GENE-041210-73	Length:	504	Species:	Danio rerio

Alignment Length:	505	Identity:	146/505 - (28%)
Similarity:	241/505 - (47%)	Gaps:	35/505 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 GIKIGNSTLCIAHVRADGKAEVIANKQGDRVSQACLLWDGASEIECGLTAKQKMANRPRQAVAHS 70
            |:..|.:..|:| |..||:|:|:||..||||:.|.:.:....:| .|:.|||.........|...
Zfish     5 GVHFGYTCACVA-VFKDGRADVVANDAGDRVTPAVVAYRDTEQI-VGIAAKQGRIRNAANTVVKV 67

  Fly    71 FQLLQPKEELTEEKLSSALREIPCDFDKEELVFRMEHTVPSDREDQDDRVVTKDLSAYQVTVELL 135
            .|:|..:.:           :......|||....:.:.....|.:.|....||.:|...|...:.
Zfish    68 KQILGRRYD-----------DPDAQAHKEESKCIVVNKSGLPRYEIDTGETTKYVSPEDVAKLIF 121

  Fly   136 RAELELAHQYHTDGEQAPIAVLSIPSYYPASAYKLLADAAQTAGFHVAQIITEPTAAVLGYSIGE 200
            ....|.|..  ..|.....||:::|..:.......|..||::|||:|.::|.||:||:|.|.||:
Zfish   122 HKMKETAQS--ALGSDVKDAVITVPFEFDEMQKNALRQAAESAGFNVLRLIHEPSAALLAYDIGQ 184

  Fly   201 EQTEQRRHVLTIKCGGLYSDIAFYSVQNGLFVQLATFGPFPIGGRQFTEALVQFICEEFRRKYKL 265
            :....:.|||..|.||....:....|.:|::..|||......||..||:.|.|.:..||::.:|.
Zfish   185 DSPLGKSHVLVYKLGGTSLSVTVLEVNSGVYRVLATQTDHQTGGESFTQELAQHLAAEFKKTFKQ 249

  Fly   266 DPHESRRSVAKIRTAAANCKHILTTMPSTQLYIDSLMDGVDYNAQMSRARFESLIQPVINNLIQQ 330
            |...:.|::.|:..:|...||.|:|:.|...::|||.||:|:...:||||||.:...:.|..||.
Zfish   250 DVSGNARAMMKLMNSADVAKHTLSTLGSANCFVDSLYDGMDFECNVSRARFELICSSLFNKCIQP 314

  Fly   331 LGECVEQAQKEHPGLSKIDDIVLLGATMQIPKLQAAVGARFPDAKLHNSHSADEVVAIGCARQAV 395
            :...:||.   :...|.::.:||.|.:.:|||||..:...|||.:|.||...|||:.:|.|.||.
Zfish   315 IKSLLEQV---NLSTSDVNKVVLSGGSARIPKLQQMIRDLFPDVELLNSIPPDEVIPVGAAMQAG 376

  Fly   396 CLIDPLEQQLHKEE---DCVVAEDDLFIWHGNDESNAK---LVLGRGSVLPAKIRISLPQSEEGK 454
            .|:......|.::.   ||..::..|   ...|:|..:   ::...|:.|||:.:.:|    :|.
Zfish   377 ILVGKDSLALGEDSITVDCCASDITL---KEVDDSGLEVFTVLFPSGTPLPARRQHTL----QGP 434

  Fly   455 GDDVSKAAASFKLRTGESEILARLPDSTIPEDGLYQLEVEVDVDDKDGNV 504
            |   |.::...:|...:..|...:.....|::.|:.: |.|....:||::
Zfish   435 G---SLSSVRLQLFQAQQPIAQIVLGDLEPKEELHDV-VTVLTMKRDGSL 480

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7182	NP_001286979.1	NBD_sugar-kinase_HSP70_actin	5..394	CDD:302596	121/387 (31%)
hspa14	NP_001038541.1	HSPA14-like_NBD	2..376	CDD:212680	122/388 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577902
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D384154at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR19375
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	5	4.900