DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7182 and hspa9

DIOPT Version :9

Sequence 1:	NP_001286979.1	Gene:	CG7182 / 38944	FlyBaseID:	FBgn0035878	Length:	513	Species:	Drosophila melanogaster
Sequence 2:	NP_958483.2	Gene:	hspa9 / 373085	ZFINID:	ZDB-GENE-030828-12	Length:	682	Species:	Danio rerio

Alignment Length:	514	Identity:	131/514 - (25%)
Similarity:	221/514 - (42%)	Gaps:	66/514 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 GIKIGNSTLCIAHVRADGK-AEVIANKQGDRVSQACLLWDGASEIECGLTAKQKMANRPRQAVAH 69
            ||.:|.:..|:|.:  ||| |:|:.|.:|.|.:.:.:.:....|...|:.||       ||||.:
Zfish    60 GIDLGTTNSCVAVM--DGKNAKVLENAEGARTTPSVVAFTSDGERLVGMPAK-------RQAVTN 115

  Fly    70 SFQLLQPKEELTEEKLSSA-----LREIPCDFDKEELVFRMEHTVPSDREDQDDRVVTKDLSAYQ 129
            ....|...:.|...:...|     |:.:|...            |.:...|....|..|..|..|
Zfish   116 PNNTLYATKRLIGRRFDDAEVQKDLKNVPYKI------------VRASNGDAWLEVHGKMYSPSQ 168

  Fly   130 VTVELLRAELELAHQYHTDGEQAPIAVLSIPSYYPASAYKLLADAAQTAGFHVAQIITEPTAAVL 194
            ....:|....|.|..|.  |:....||:::|:|:..|..:...||.|.||.:|.::|.|||||.|
Zfish   169 AGAFILIKMKETAESYL--GQSVKNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVINEPTAAAL 231

  Fly   195 GYSIGEEQTEQRRHVLTIKCGGLYSDIAFYSVQNGLFVQLATFGPFPIGGRQFTEALVQFICEEF 259
            .|.:.:.|.   :.:.....||...||:...:|.|:|...:|.|...:||..|.:.|::.|.:||
Zfish   232 AYGLDKTQD---KIIAVYDLGGGTFDISVLEIQKGVFEVKSTNGDTFLGGEDFDQHLLRHIVKEF 293

  Fly   260 RRKYKLDPHESRRSVAKIRTAAANCKHILTTMPSTQLYIDSL-MDG---VDYNAQMSRARFESLI 320
            :::..:|..:...::.::|.||...|..|::...|.:.:..| ||.   ...|.:::|::||.::
Zfish   294 KKESGVDLMKDNMALQRVREAAEKAKCELSSSLQTDINLPYLTMDASGPKHLNMKLTRSQFEGIV 358

  Fly   321 QPVINNLIQQLGECVEQAQKEHPGLSKIDDIVLLGATMQIPKLQAAVGARFPDAKLHNSHSADEV 385
            ..:|...:   ..|.:..|......|.|.:::|:|...::||:|..|...|..|. ..|.:.||.
Zfish   359 ADLIRRTV---APCQKAMQDAEVSKSDIGEVLLVGGMTRMPKVQQTVQDLFGRAP-SKSVNPDEA 419

  Fly   386 VAIGCARQA---------VCLIDPLEQQLHKEEDCVVAEDDLFIWHGNDESNAKLVLGRGSVLPA 441
            ||||.|.|.         |.|:|.....|..|     ....:|         .||: .|.:.:|.
Zfish   420 VAIGAAIQGGVLAGDVTDVLLLDVTPLSLGIE-----TLGGVF---------TKLI-NRNTTIPT 469

  Fly   442 KIRISLPQSEEGKGDDVSKAAASFKLRTGESEILARLPDSTIPE--DGLYQLEVEVDVD 498
            |.......:.:|:.....|.....:....::::|.:.....||.  .|:.|:||..|:|
Zfish   470 KKSQVFSTAADGQTQVEIKVCQGEREMATDNKVLGQFTLVGIPPALRGVPQIEVTFDID 528

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7182	NP_001286979.1	NBD_sugar-kinase_HSP70_actin	5..394	CDD:302596	108/397 (27%)
hspa9	NP_958483.2	HSPA9-like_NBD	55..431	CDD:212683	109/400 (27%)
hspa9	NP_958483.2	dnaK	56..659	CDD:234715	131/514 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900