Protein Alignment CG7182 and HSPA1B

DIOPT Version :9

• Sequence 1: NP_001286979.1
• Gene: CG7182 / 38944
• FlyBaseID: FBgn0035878
• Length: 513
• Species: Drosophila melanogaster
• Sequence 2: NP_005337.2
• Gene: HSPA1B / 3304
• HGNCID: 5233
• Length: 641
• Species: Homo sapiens
• Alignment Length: 526
• Identity: 145/526 - (27%)
• Similarity: 239/526 - (45%)
• Gaps: 85/526 - (16%)

  Fly     6 GIKIGNSTLCIAHVRADGKAEVIANKQGDRVSQACLLWDGASEIECGLTAKQKMANRPRQAVAHS 70
            ||.:|.:..|:. |...||.|:|||.||:|.:.:.:.:.....: .|..||.::|..|:..|
Human     8 GIDLGTTYSCVG-VFQHGKVEIIANDQGNRTTPSYVAFTDTERL-IGDAAKNQVALNPQNTV--- 67

  Fly    71 FQLLQPKEELTEEKLSSALREIPCDFDKEELVFRM--EHTVPSDREDQDDRVV------------ 121
                                     ||.:.|:.|.  :..|.||.:....:|:
Human    68 -------------------------FDAKRLIGRKFGDPVVQSDMKHWPFQVINDGDKPKVQVSY 107

  Fly   122 ---TKDLSAYQVTVELLRAELELAHQYHTDGEQAPIAVLSIPSYYPASAYKLLADAAQTAGFHVA 183
               ||.....:::..:|....|:|..|.  |.....||:::|:|:..|..:...||...||.:|.
Human   108 KGETKAFYPEEISSMVLTKMKEIAEAYL--GYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVL 170

  Fly   184 QIITEPTAAVLGYSIGEEQTEQRRHVLTIKCGGLYSDIAFYSVQNGLFVQLATFGPFPIGGRQFT 248
            :||.|||||.:.|.: :...:..|:||....||...|::..::.:|:|...||.|...:||..|.
Human   171 RIINEPTAAAIAYGL-DRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFD 234

  Fly   249 EALVQFICEEFRRKYKLDPHESRRSVAKIRTAAANCKHILTTMPSTQLYIDSLMDGVDYNAQMSR 313
            ..||....|||:||:|.|..:::|:|.::|||....|..|::.....|.||||.:|:|:...::|
Human   235 NRLVNHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSSSTQASLEIDSLFEGIDFYTSITR 299

  Fly   314 ARFESLIQPVINNLIQQLGECVEQAQKEHPGLSKIDDIVLLGATMQIPKLQAAVGARFPDAKLHN 378
            ||||.|...:..:.::.:.:.:..|:.:.   ::|.|:||:|.:.:|||:|..:...|....|:.
Human   300 ARFEELCSDLFRSTLEPVEKALRDAKLDK---AQIHDLVLVGGSTRIPKVQKLLQDFFNGRDLNK 361

  Fly   379 SHSADEVVAIGCARQAVCLIDPLEQQLHKEEDCVVAEDDLFIWHGNDESNAKLVLG--------- 434
            |.:.||.||.|.|.||..|:.      .|.|:   .:|.|.:      ..|.|.||
Human   362 SINPDEAVAYGAAVQAAILMG------DKSEN---VQDLLLL------DVAPLSLGLETAGGVMT 411

  Fly   435 ----RGSVLPAK-IRISLPQSEEGKGDDVSKAAASFKLRTGESEILARLPDSTIP--EDGLYQLE 492
                |.|.:|.| .:|....|:...| .:.:.....:..|.::.:|.|...|.||  ..|:.|:|
Human   412 ALIKRNSTIPTKQTQIFTTYSDNQPG-VLIQVYEGERAMTKDNNLLGRFELSGIPPAPRGVPQIE 475

  Fly   493 VEVDVD 498
            |..|:|
Human   476 VTFDID 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7182	NP_001286979.1	NBD_sugar-kinase_HSP70_actin	5..394	CDD:302596	115/404 (28%)
HSPA1B	NP_005337.2	PTZ00009	1..611	CDD:240227	145/526 (28%)
		Nucleotide-binding domain (NBD). /evidence=ECO:0000250|UniProtKB:P11142	2..386		119/419 (28%)
		Substrate-binding domain (SBD). /evidence=ECO:0000250|UniProtKB:P11142	394..509		23/95 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	614..641

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810