DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7182 and Hspa4

DIOPT Version :9

Sequence 1:NP_001286979.1 Gene:CG7182 / 38944 FlyBaseID:FBgn0035878 Length:513 Species:Drosophila melanogaster
Sequence 2:NP_705893.1 Gene:Hspa4 / 266759 RGDID:628878 Length:840 Species:Rattus norvegicus


Alignment Length:528 Identity:122/528 - (23%)
Similarity:213/528 - (40%) Gaps:88/528 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 GIKIGNSTLCIAHVRADGKAEVIANKQGDRVSQACLLWDGASEIECGLTAKQKMANRPRQAVA-- 68
            ||.:|..:..:|..||.| .|.|||:..||.:.||:.: |......|..||.::.:..:..|.  
  Rat     5 GIDLGFQSCYVAVARAGG-IETIANEYSDRCTPACVSF-GPKNRSVGAAAKSQVISNAKNTVQGF 67

  Fly    69 ---HSFQLLQPKEELTEEKLSSALREIPCDFDKEELVFRMEHTVPSDREDQDDRVVTKDLSAYQV 130
               |......|..|..:..|:..:.::|......::.:..|.               ::.:..||
  Rat    68 KRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEE---------------RNFTTEQV 117

  Fly   131 TVELLRAELELAHQYHTDGEQAPI--AVLSIPSYYPASAYKLLADAAQTAGFHVAQIITEPTAAV 193
            |..||....|.|...    .:.|:  .|:|:||:|..:..:.:.||.|.||.:..:::.|.||..
  Rat   118 TAMLLSKLKETAESV----LKKPVVDCVVSVPSFYTDAERRSVMDATQIAGLNCLRLMNETTAVA 178

  Fly   194 LGYSIGEEQ----TEQRRHVLTIKCGGLYSDIAFYSVQNGLFVQLATFGPFPIGGRQFTEALVQF 254
            |.|.|.::.    .|:.|:|:.:..|.....::..:...|....|||.....:|||:|.|.||..
  Rat   179 LAYGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVLVNH 243

  Fly   255 ICEEFRRKYKLDPHESRRSVAKIRTAAANCKHILTTMPS-TQLYIDSLMDGVDYNAQMSRARFES 318
            .||||.:|||||.....|::.::.......|.:::...| ..|.|:..|:.:|.:..|:|.:|..
  Rat   244 FCEEFGKKYKLDIKSKVRALLRLSQECEKLKKLMSANASDLPLSIECFMNDIDVSGTMNRGKFLE 308

  Fly   319 L-------IQPVINNLIQQLGECVEQAQKEHPGLSKIDDIVLLGATMQIPKLQAAVGARFPDAKL 376
            :       ::|.:.:::.|     .:.:||     .|..:.::|...:||.::..: ::|...:|
  Rat   309 MCDDLLARVEPPLRSILDQ-----SKLKKE-----DIYAVEIVGGATRIPAVKEKI-SKFFGKEL 362

  Fly   377 HNSHSADEVVAIGCARQAVCLIDPLEQQLHKEEDCVVAEDDLFIWHGNDESNAKLVLGRGSVLPA 441
            ..:.:|||.|..|||.|...|....:.:.....|.|                         ..|.
  Rat   363 STTLNADEAVTRGCALQCAILSPAFKVREFSITDVV-------------------------PYPI 402

  Fly   442 KIRISLPQSEEGKGD----------DVSKAAASFKLRTGESEILARLP-DSTIPEDGLYQLEVEV 495
            .:|.:.| :|||..|          ..||....::......|.....| |...|:..:.|..|:.
  Rat   403 SLRWNSP-AEEGSSDCEVFPKNHAAPFSKVLTFYRKEPFTLEAYYSSPQDLPYPDPAIAQFSVQK 466

  Fly   496 DVDDKDGN 503
            .....||:
  Rat   467 VTPQSDGS 474

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG7182NP_001286979.1 NBD_sugar-kinase_HSP70_actin 5..394 CDD:302596 101/406 (25%)
Hspa4NP_705893.1 HSPA4_NBD 2..384 CDD:212687 102/410 (25%)
PTZ00121 <499..743 CDD:173412
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 500..575
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 781..840
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0443
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.900

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