DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7182 and ssa1

DIOPT Version :9

Sequence 1:	NP_001286979.1	Gene:	CG7182 / 38944	FlyBaseID:	FBgn0035878	Length:	513	Species:	Drosophila melanogaster
Sequence 2:	NP_593704.1	Gene:	ssa1 / 2542875	PomBaseID:	SPAC13G7.02c	Length:	644	Species:	Schizosaccharomyces pombe

Alignment Length:	525	Identity:	132/525 - (25%)
Similarity:	232/525 - (44%)	Gaps:	83/525 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 GIKIGNSTLCIAHVRADGKAEVIANKQGDRVSQACLLWDGASEIECGLTAKQKMANRPRQAVAHS 70
            ||.:|.:..|:.|. ::.:.|:|||.||:|.:.:.:.:.....: .|..||.::|..|...:
pombe     6 GIDLGTTYSCVGHF-SNNRVEIIANDQGNRTTPSYVAFTDTERL-IGDAAKNQVAMNPHNTI--- 65

  Fly    71 FQLLQPKEELTEEKLSSALREIPCDFDKEELVFRM--EHTVPSDREDQDDRVVTKD--------- 124
                                     ||.:.|:.|.  :..|.||.:....:|:.||
pombe    66 -------------------------FDAKRLIGRRFNDPEVQSDMKHWPFKVIEKDGKPLIQVEF 105

  Fly   125 ------LSAYQVTVELLRAELELAHQYHTDGEQAPIAVLSIPSYYPASAYKLLADAAQTAGFHVA 183
                  .:..:::..:|....|.|..:.  |.:...||:::|:|:..|..:...||...||.:|.
pombe   106 KGETKTFTPEEISSMVLLKMRESAEAFL--GGKVTDAVVTVPAYFNDSQRQATKDAGLIAGLNVL 168

  Fly   184 QIITEPTAAVLGYSIGEEQTEQRRHVLTIKCGGLYSDIAFYSVQNGLFVQLATFGPFPIGGRQFT 248
            :||.|||||.:.|.: :...:...:||....||...|::..:::.|:|...||.|...:||..|.
pombe   169 RIINEPTAAAIAYGL-DRSNQHETNVLIFDLGGGTFDVSLLTIEEGIFEVKATAGDTHLGGEDFD 232

  Fly   249 EALVQFICEEFRRKYKLDPHESRRSVAKIRTAAANCKHILTTMPSTQLYIDSLMDGVDYNAQMSR 313
            ..||....:||:||.|.|...:.|:|.::|||....|..|::.....:.||||.:|:|:...::|
pombe   233 SRLVNHFAQEFKRKNKKDITGNARAVRRLRTACERAKRTLSSSAQASIEIDSLYEGIDFYTSITR 297

  Fly   314 ARFESLIQPVINNLIQQLGECVEQAQKEHPGLSKIDDIVLLGATMQIPKLQAAVGARFPDAKLHN 378
            ||||.|...:..|.::.:.:.:..::.:.   |.:::|||:|.:.:||::|..|...|...:...
pombe   298 ARFEELCADLFRNTMEPVEKVLRDSKIDK---SSVNEIVLVGGSTRIPRIQKLVSDFFNGKEPCK 359

  Fly   379 SHSADEVVAIGCARQAVCLIDPLEQQLHKEEDCVVAEDDLFIWHGNDESNAKLVLG--------- 434
            |.:.||.||.|.|.||..|:....:   |.:|.::.:            .|.|.||
pombe   360 SINPDEAVAYGAAVQAAILVGDTSE---KTQDLLLLD------------VAPLSLGIETAGGVMT 409

  Fly   435 ----RGSVLPAKIRISLPQSEEGKGDDVSKAAASFKLRTGESEILARLPDSTIP--EDGLYQLEV 493
                |.:.:|.|.........:.:...:.:.....:.||.:..:|.:...|.||  ..|:.|:||
pombe   410 PLIKRNTTIPTKKSEVFSTYADNQPGVLIQVFEGERARTKDCNLLGKFELSGIPPAPRGVPQIEV 474

  Fly   494 EVDVD 498
            ..|||
pombe   475 TFDVD 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7182	NP_001286979.1	NBD_sugar-kinase_HSP70_actin	5..394	CDD:302596	107/404 (26%)
ssa1	NP_593704.1	PTZ00009	4..644	CDD:240227	132/525 (25%)
ssa1	NP_593704.1	HSPA1-2_6-8-like_NBD	4..378	CDD:212675	109/407 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0443
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810